ID A0A0T5P1P6_9RHOB Unreviewed; 545 AA.
AC A0A0T5P1P6;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:KRS15030.1};
DE EC=1.1.99.1 {ECO:0000313|EMBL:QEW25351.1};
GN Name=betA_3 {ECO:0000313|EMBL:QEW25351.1};
GN ORFNames=RIdsm_01137 {ECO:0000313|EMBL:QEW25351.1}, XM52_26030
GN {ECO:0000313|EMBL:KRS15030.1};
OS Roseovarius indicus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=540747 {ECO:0000313|EMBL:KRS15030.1, ECO:0000313|Proteomes:UP000051401};
RN [1] {ECO:0000313|EMBL:KRS15030.1, ECO:0000313|Proteomes:UP000051401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B108 {ECO:0000313|EMBL:KRS15030.1,
RC ECO:0000313|Proteomes:UP000051401};
RA Li G., Lai Q., Shao Z., Yan P.;
RT "The draft genome sequence of Roseovarius indicus B108T.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QEW25351.1, ECO:0000313|Proteomes:UP000325785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 26383 {ECO:0000313|EMBL:QEW25351.1,
RC ECO:0000313|Proteomes:UP000325785};
RA Vollmers J., Petersen J.;
RT "Genetic Globetrotter - A new plasmid hitch-hiking vast phylogenetic and
RT geographic distances.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790, ECO:0000256|RuleBase:RU003968}.
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DR EMBL; LAXI01000029; KRS15030.1; -; Genomic_DNA.
DR EMBL; CP031598; QEW25351.1; -; Genomic_DNA.
DR RefSeq; WP_057821094.1; NZ_LAXI01000029.1.
DR AlphaFoldDB; A0A0T5P1P6; -.
DR STRING; 540747.SAMN04488031_106238; -.
DR KEGG; rid:RIdsm_01137; -.
DR PATRIC; fig|540747.5.peg.3567; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000051401; Unassembled WGS sequence.
DR Proteomes; UP000325785; Chromosome.
DR GO; GO:0008812; F:choline dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00623; GMC_OXRED_1; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU003968};
KW Oxidoreductase {ECO:0000313|EMBL:QEW25351.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000051401}.
FT DOMAIN 84..107
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00623"
FT DOMAIN 256..270
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 86
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 221
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 545 AA; 60966 MW; EBAAE526E5F7C636 CRC64;
MTKTRTTDYL VIGAGSAGSA VAARLAEDEN TTVTLLEAGP TDRHPYIMMP AAMGYNLVSD
RRNWFYRTQP EPHLDNRTVM QARGRVLGGS SSINGMNWVR GNPLDYDEWA NMGLKSWGYE
SVLPYFKRAE TFDRGGNDYR GDSGPMRVQS CAGKNPLYET FLEAGQEMGL PYLDDHNAYR
QEGVFHGQRN VHDGIRWNTY QGFVRSQAAK PNLTVEKNAR VLKIETSNKR VVRIQAKIDG
IRQTFEVEKE TILCAGALNS PQLLNLSGIG HADDLKAADI PLTHHLPGVG RNLQDHLSID
IQYHTTKNVS IAHDLNLLGQ AKAGLQWLLF KKGIGVSNFF EVGAFIRTRE SEKIANMQVE
FIPMMAEFTD DNFAALPGFQ GYLTLQRPGS RGRVWVDSAD PMASPKFRFN YYEDPDDLEQ
ALEMVKTMRT LIKQSAWDEL RGAEVMPGPD VQTDDEIRAW LRTITATNYH PCGTCRMGHD
DDAVVDEEGR VHGLEALRVV DASIMPKIVT GNLNCPTIMM AEKISDSIRG RAPLPPEPQP
YYTAH
//
