ID A0A0T5XCF0_9BACT Unreviewed; 408 AA.
AC A0A0T5XCF0;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative 23S rRNA methyltransferase {ECO:0000313|EMBL:KRT35429.1};
GN ORFNames=HMPREF1705_02655 {ECO:0000313|EMBL:KRT35429.1};
OS Acetomicrobium hydrogeniformans ATCC BAA-1850.
OC Bacteria; Synergistota; Synergistia; Synergistales; Acetomicrobiaceae;
OC Acetomicrobium.
OX NCBI_TaxID=592015 {ECO:0000313|EMBL:KRT35429.1, ECO:0000313|Proteomes:UP000005273};
RN [1] {ECO:0000313|EMBL:KRT35429.1, ECO:0000313|Proteomes:UP000005273}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1850 {ECO:0000313|Proteomes:UP000005273};
RA Gruening B.A., Erxleben A., Flemming S., Lucas X., Doering K.,
RA Weitnauer G., Bechthold A., Guenther S.;
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RlmI family.
CC {ECO:0000256|ARBA:ARBA00038091}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRT35429.1}.
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DR EMBL; ACJX03000001; KRT35429.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0T5XCF0; -.
DR STRING; 592015.HMPREF1705_02655; -.
DR eggNOG; COG1092; Bacteria.
DR Proteomes; UP000005273; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd21153; PUA_RlmI; 1.
DR CDD; cd11572; RlmI_M_like; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR Gene3D; 3.30.750.80; RNA methyltransferase domain (HRMD) like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR041532; RlmI-like_PUA.
DR InterPro; IPR019614; SAM-dep_methyl-trfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42873:SF1; METHYLTRANS_SAM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42873; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE; 1.
DR Pfam; PF10672; Methyltrans_SAM; 1.
DR Pfam; PF17785; PUA_3; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KRT35429.1}; RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KRT35429.1}.
FT DOMAIN 19..103
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 408 AA; 45859 MW; 6FD727E12945DD12 CRC64;
MKCGSFLPWE GVKCIMALNS LYVKKGFEQS IHEGHPWIYK NAINRIRGDF TPGDLVEIKD
WRGKFLGIGY ANPSSYIVAR ILTRKQERID ERFWRKRLKS ALNFRSKTGI AELDAYRMVF
SEADFLPGVI IDKFGDYIVL QTLTLGMDRF KEIIVRVLTD LFPVKGIYHK NDVPVRAIEG
LSQEDCLLFG EVPDEVIIEE NGVKFCVNIA GGQKTGHFLD QRRNRVLLKD ISKGADVLDA
FCYTGGFGLN AARFGAKTVF GVDVSEDAVA TARRNAGLNG FDAVCRYDVA NVFDRLRELE
PKGQRYDVIV LDPPAFAKNK KAVEGALRGY KEINLRAMKI IKEGGFLLTC SCSHHISWDL
FEGVIFEAAK DAGKTLRVVA REGQPPDHPV LMGFDESLYL KCLLLEVS
//
