ID A0A0T5ZTQ7_9BACT Unreviewed; 1238 AA.
AC A0A0T5ZTQ7;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:KRT66021.1};
GN ORFNames=XU11_C0015G0038 {ECO:0000313|EMBL:KRT66021.1};
OS Candidatus Dadabacteria bacterium CSP1-2.
OC Bacteria; Thermodesulfobacteriota; Candidatus Dadabacteria.
OX NCBI_TaxID=1640508 {ECO:0000313|EMBL:KRT66021.1, ECO:0000313|Proteomes:UP000051780};
RN [1] {ECO:0000313|EMBL:KRT66021.1, ECO:0000313|Proteomes:UP000051780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSP1-2 {ECO:0000313|EMBL:KRT66021.1};
RA Hug L.A., Thomas B.C., Sharon I., Brown C.T., Sharma R., Hettich R.L.,
RA Wilkins M.J., Williams K.H., Singh A., Banfield J.F.;
RT "Critical biogeochemical functions in the subsurface are associated with
RT bacteria from new phyla and little studied lineages.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRT66021.1}.
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DR EMBL; LDXN01000015; KRT66021.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0T5ZTQ7; -.
DR STRING; 1640508.XU11_C0015G0038; -.
DR PATRIC; fig|1640508.3.peg.1074; -.
DR Proteomes; UP000051780; Unassembled WGS sequence.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR025874; DZR.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF12773; DZR; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF13424; TPR_12; 4.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00028; TPR; 11.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50005; TPR; 5.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 91..223
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT REPEAT 824..857
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 864..897
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1067..1100
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1147..1180
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1187..1220
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 1238 AA; 140051 MW; 6FD83C8CAA9CABAD CRC64;
MKCSNCQSDN PNEARFCGEC GAKLEIKCQS CGKENPPINK FCYECGHKLS ESVKPAQVLN
LDQPQSYIPK HLAEKILVGK ASLEGERKQV TVLFADASGF TALSEKIDPE EVRSLMNNCL
RLVIEEVHNY EGTINKFTGD GVMALFGAPI ALEDHPYRAV SAALRIQESL KSFSEEIKRE
RGIDFKMRIG INTGLVVVGS IGNDLSMEYT AMGDTVNLAS RLEGLAEPGT ILISENTYRL
VKDYFEFKPI GEIQVKGKSE PVKAYSAIGL TRIKGRFEIS LERGLTKFVG REKELELIKD
SLEKVKEGKG QIVCVIGEAG IGKSRLIHEF KSSIRDEEIN YLEGHCISYG KSFSYLPIVE
ILKNNFTVDD RDDDELIKAK VETAINKMDS KLKDTIPIIL DLLSVKTDFD ILKDLDAGQK
RQGIFEALKA ITLRGSQIRP LVILIEDLHW IDKTSEDFIN YLSGSVGNQR IMLLFTCRTG
FVHSFIYNPY YTQIALTSLS TRECRVLIES TLLGENIPED LMRLILERTG GNAFFVEEVT
KSLLDTGIII KSESGYMMNK NASQIDVPST IQDVIMARID RLEENRKRAL QVGSVIGREF
SYELLKKVSS LDDNELRDHL LTLINLELIY ERGIFPDTNY VFKHALTHEV AYASLLVQKR
KEIHERVGSA VEELYPNRLE EFYEVLAHHY NRADDKEKGL HYLTLAGKKA KEVVATEEAL
NYFREALKRL DEMPETETNE ERKIDILFEM ENIYDHIGKR EEQKKILERI IDSSGVINDE
RRLSDGYIKQ AEFLSVLEEY QKAQEVGESA LTLKRKIGDK LGQGKALRGM GFINWRSGDY
ESALKYHQEA LSVHRELGGG EAEGFELISL GEMHRKLGQY EDALSCLQEA LRIYRELGIS
SGQHVSTFNI GSVYRDMGDY QACLEYYQEC WRIIKARGYS SLSGVIAAAS GLADIYLLLG
NYQESLRYYS EALDIIRGLG DRSEEGNILS YMAAIYGILA DYQQSVNHYK EALNIYRELG
DKSSEGRVLT LIGNIYRQNL HDYNRAISFY KEGLEIKKEI EDISEIRSLS NSLGIACWNL
GHYEEALAYY QDALEICKNT GNMLGEGITL SGMGVVYLSL CNYEEALKCN MDALNILKAT
GDLKVEGYIL NSIGNVYYEI GDYQRAWKYY QESLKIRKEL GDKKGEAWVL HNLGRVYRGL
ENYEEAKKCY KQALSLAEEV GEGELVANSK NALSEIKK
//
