ID A0A0T6AU62_9SCAR Unreviewed; 742 AA.
AC A0A0T6AU62;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Rab5 GDP/GTP exchange factor {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMK59_7448 {ECO:0000313|EMBL:KRT78427.1};
OS Oryctes borbonicus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Scarabaeiformia;
OC Scarabaeidae; Dynastinae; Oryctes.
OX NCBI_TaxID=1629725 {ECO:0000313|EMBL:KRT78427.1, ECO:0000313|Proteomes:UP000051574};
RN [1] {ECO:0000313|EMBL:KRT78427.1, ECO:0000313|Proteomes:UP000051574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OB123 {ECO:0000313|EMBL:KRT78427.1};
RC TISSUE=Whole animal {ECO:0000313|EMBL:KRT78427.1};
RA Meyer J.M., Markov G.V., Baskaran P., Herrmann M., Sommer R.J.,
RA Roedelsperger C.;
RT "Draft genome of the scarab beetle Oryctes borbonicus.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRT78427.1}.
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DR EMBL; LJIG01022843; KRT78427.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0T6AU62; -.
DR OrthoDB; 20678at2759; -.
DR Proteomes; UP000051574; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.10.246.120; -; 1.
DR Gene3D; 1.20.5.4770; -; 1.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR InterPro; IPR041545; DUF5601.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR045046; Vps9-like.
DR InterPro; IPR037191; VPS9_dom_sf.
DR InterPro; IPR002653; Znf_A20.
DR PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23101:SF122; RAB5 GDP_GTP EXCHANGE FACTOR; 1.
DR Pfam; PF18151; DUF5601; 1.
DR Pfam; PF02204; VPS9; 1.
DR Pfam; PF01754; zf-A20; 1.
DR SMART; SM00167; VPS9; 1.
DR SMART; SM00259; ZnF_A20; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR PROSITE; PS51205; VPS9; 1.
DR PROSITE; PS51036; ZF_A20; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000051574};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 12..46
FT /note="A20-type"
FT /evidence="ECO:0000259|PROSITE:PS51036"
FT DOMAIN 213..356
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT REGION 44..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 83348 MW; 87A3F1E043799253 CRC64;
MYATKQPSLR IKQADLKCKN GCGYYGNPDW GGYCSKCYRS SMEKDRHHRK SDHSRSPVPG
FSKFEEKKRQ QTDKKSKYLS FAPVVFRRTS AAKDVGRPER HHEPRHTNPE MEKLELEYMS
TYIHLGRHVR DDFFKFVKFF NVNIRNEMNS RPIEEVAVVA QKYYNFFANR INSHEIYSKM
EQETKDHLID FFEKFSMTTL YSILFCPHTT NDEEKDLAIQ RRIRQLSWVN AHHLDCCISE
TSMEVRDLVY AAITHLLGMD SVKAPQEKLS YVVRCCQSVV EVLRHCQGGP VSADEFLPAL
IFVVLKANPA RLKSNILYVT RFCNDARLMQ GEGGYYFTNL CCAVSFIENL TAESLNMSEE
EFQGYMTGTI TSVSAWESAL VACEGMHQLC EHLAELKGLS ERMDSVQEGT LNLRETMEAF
KKEINAKVIE IRESTPLIIK PRKIPISLDK QDSNAANLPS PLAPTVVNSS SILSEQSEPI
TIPITIDTVA DETDETTTQT HFYTQNLATQ ELNLMDSKKG KLQLDITPCL PTETLKQSQS
NELLAYDTQS LDGFITPDDG SLLGLSNINY DIDLSDLSAD NSVADELTPE KKKSPNFMVD
PFSPLSGPCN ISQSPLIPSS ATDAPIASSS TSRELTNDNF VLPFKTEDSS LLNTQGNASI
VHLPSPIKPH TPHYSGFSMQ GVQIPSIPCN TGDYSSLNLV QQRESEATTS GIGDNSKKEE
NKSNEKVVKV LGGVLDTIDK LF
//
