ID A0A0T6B0A2_9SCAR Unreviewed; 406 AA.
AC A0A0T6B0A2;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=WD40 domain-containing protein {ECO:0000313|EMBL:KRT80533.1};
GN ORFNames=AMK59_6737 {ECO:0000313|EMBL:KRT80533.1};
OS Oryctes borbonicus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Scarabaeiformia;
OC Scarabaeidae; Dynastinae; Oryctes.
OX NCBI_TaxID=1629725 {ECO:0000313|EMBL:KRT80533.1, ECO:0000313|Proteomes:UP000051574};
RN [1] {ECO:0000313|EMBL:KRT80533.1, ECO:0000313|Proteomes:UP000051574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OB123 {ECO:0000313|EMBL:KRT80533.1};
RC TISSUE=Whole animal {ECO:0000313|EMBL:KRT80533.1};
RA Meyer J.M., Markov G.V., Baskaran P., Herrmann M., Sommer R.J.,
RA Roedelsperger C.;
RT "Draft genome of the scarab beetle Oryctes borbonicus.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC Endosome {ECO:0000256|ARBA:ARBA00004177}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRT80533.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LJIG01022450; KRT80533.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0T6B0A2; -.
DR OrthoDB; 5385125at2759; -.
DR Proteomes; UP000051574; Unassembled WGS sequence.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15718; FYVE_WDFY1_like; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR042234; WDFY1/WDFY2.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46189; LD41958P; 1.
DR PANTHER; PTHR46189:SF1; LD41958P; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000051574};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT REPEAT 202..235
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 245..286
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 288..359
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REPEAT 369..406
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 406 AA; 45467 MW; 7E89B873B28598CB CRC64;
MAAEIKPATQ SNDKFCTTKK PQLLAKLEGC NDEINAAVIL PGEDGVISVS DDKTVRVWLK
RDSGQYWPSI CQYMPSGATS LSYTAETRQL FIGQENGTVS EYTLASDFNR MMPVREYLAH
QARVAEVLFA LNCEWVLSVS RDKVFSYNCT QTGRNIGTFM TEAWCSALQF DNQTKHAFVG
DYSGQITMLK LSNNGASVIT TLKGHAGSVR TLAWDAERQM LFSGSFDHMV IVWDIGGQQG
NAYELQGHQN KVTALCYLSG TKQLVSAGED GVIVFWDMNQ QRKETPEWSE SDSCQLCSRP
FFWNLRAMMD QRQLGLRQHH CRHCGKAVCD RCSSGRLSIP VMGFEFAVRV CEPCHLSLKD
ADRPSLATFH DPKHSVLAMN VDETRSKLLT VGQDRLIKIW DISALL
//
