ID A0A0T6B1Z8_9SCAR Unreviewed; 912 AA.
AC A0A0T6B1Z8;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};
GN ORFNames=AMK59_4998 {ECO:0000313|EMBL:KRT81420.1};
OS Oryctes borbonicus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Scarabaeiformia;
OC Scarabaeidae; Dynastinae; Oryctes.
OX NCBI_TaxID=1629725 {ECO:0000313|EMBL:KRT81420.1, ECO:0000313|Proteomes:UP000051574};
RN [1] {ECO:0000313|EMBL:KRT81420.1, ECO:0000313|Proteomes:UP000051574}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OB123 {ECO:0000313|EMBL:KRT81420.1};
RC TISSUE=Whole animal {ECO:0000313|EMBL:KRT81420.1};
RA Meyer J.M., Markov G.V., Baskaran P., Herrmann M., Sommer R.J.,
RA Roedelsperger C.;
RT "Draft genome of the scarab beetle Oryctes borbonicus.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|RuleBase:RU003844}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRT81420.1}.
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DR EMBL; LJIG01016165; KRT81420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0T6B1Z8; -.
DR OrthoDB; 960at2759; -.
DR Proteomes; UP000051574; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13287; PH_ORP3_ORP6_ORP7; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR018494; Oxysterol-bd_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041680; PH_8.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972:SF216; OXYSTEROL-BINDING PROTEIN HOMOLOG 3; 1.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15409; PH_8; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01013; OSBP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055,
KW ECO:0000256|RuleBase:RU003845};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000051574};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003845}.
FT DOMAIN 89..184
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 912 AA; 102142 MW; 20B76B1CA0372D86 CRC64;
MEKKKISMSN KIGGGSAGKI KASNLGINTS DSEASVDTNS LSADSATEQQ QQPPTQPPKP
PTRKKNHRRS SEWEIMEGLK EGQKCEKKPA KYSGYLHKKR KWPLKGWHKR YFVLDDGILV
YGKGPSEIGK GKLHGSVDIG LSVISSKAKR RRIDIDAEEF IYHLKAKTEE TFTAWVQQLT
EHRLYRQHVL SYGKGGYSNS TSDERKMPLT PEIASRDGSL TRGLKPIGSI RLSTWLHDSG
SVLEQMQRDL GLIELNLNEL KRFWQAIDCH SPYLLTNSVG GETESLGEGL SPNVKKGKKF
GLKKKKSSKG GSVDLTMSFN RASMIDSDNT SPLSQNASVS NTNISNLGTT ITVNQALSLP
CDHFSNADKH SYGVPDNQNK EDFVALAKNV LAGLKSVASS LSTERDRLKA AIDVESGLQN
LNDLSSLDPV SDTHRQFNNS LSYSSSCMSC SEFFDAEDIA GEKNTAVAVA ADIGDENQVE
DLEAEIRTRG SDSSSEAGSL SSGEGSISSE SDLGADYNQT SNLSEIEGAS LQQGLTGRRT
TLPFPRPDTE GLSLWNLLCK NIGKDLSQIS MPVALNEPLN MLQRLCEDLE YSELLDKAAD
IDDPYERMVY VAAFAVSAYA NSYSRAGNKP FNPLLGETYE CIREDRGFRF IAEQVSHHPP
ISACHAESRN FTFWQEARIK TKFWGKSMEF QPMGQVHVLL PRTGDLYSWN KVTTCVHNLF
SSQRWVDQYG ELHITNGRIS CRLTFAKASY WSAKRHEVLG AVYNESGDPV YRLFGKWSEA
LYCGVAPAAK CIWRAGTMPP DHERYYGFTR YAIELNERGP DAHLLPPTDT RFRPDQRALE
NGDLQLAETL KMQLEAVQRD RRKKREEKNV AYEPLWFSHK KDEKEDLWEY NGKYWEVRKN
RGFVGMLFEP LW
//
