ID A0A0T6UM45_9PSED Unreviewed; 919 AA.
AC A0A0T6UM45;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN ORFNames=AO726_14805 {ECO:0000313|EMBL:KRW58787.1};
OS Pseudomonas sp. TTU2014-080ASC.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1729724 {ECO:0000313|EMBL:KRW58787.1, ECO:0000313|Proteomes:UP000051864};
RN [1] {ECO:0000313|EMBL:KRW58787.1, ECO:0000313|Proteomes:UP000051864}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TTU2014-080ASC {ECO:0000313|EMBL:KRW58787.1,
RC ECO:0000313|Proteomes:UP000051864};
RA Webb H.E., Bugarel M., Den Bakker H.C., Nightingale K., Granier S.A.,
RA Loneragan G.H.;
RT "Carbapenem-non-susceptible Bacteria Recovered from the Faeces of Dairy
RT Cattle.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRW58787.1}.
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DR EMBL; LKKK01000012; KRW58787.1; -; Genomic_DNA.
DR RefSeq; WP_058068897.1; NZ_LKKK01000012.1.
DR AlphaFoldDB; A0A0T6UM45; -.
DR STRING; 1729724.AO726_14805; -.
DR Proteomes; UP000051864; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW Rule:MF_01411};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW Reference proteome {ECO:0000313|Proteomes:UP000051864};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT CHAIN 34..919
FT /note="LPS-assembly protein LptD"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT /id="PRO_5008995897"
FT DOMAIN 150..283
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT DOMAIN 395..825
FT /note="LptD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04453"
FT REGION 54..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 919 AA; 104203 MW; 2DC1499506F3ED6F CRC64;
MAVKYPAFRR KFPLLVTGGM LALQPVAIPF AVAAEQFDCQ VSASGGWACA PKTNNAALPA
RPQPREAVAS TDESKSGSGK KAAQTMLVTE SRGKALASRS ADYSHLDWVP REQLTPAQLA
EAGPYCSGAY IEPQRPGMDD TTPMSQAPMY VSAKASRYEQ EQQIATLAGD VVLRQSSMQV
EADEANLHQA ENLGELVGNV RLRDKGALVV GDRAELQLDS GEARIDNAEY VLHQSHIRGN
ALYAKREESA IIRLKDGTYT SCEPGSNSWH LKGNNITLNP ATGFGTATNV TLRVKNIPVF
YTPYIYFPID DRRQSGFLPP TIASSSDNGF TLKTPYYFNL APNYDATLYP TYMADRGLLM
EGEFRYLTKS SEGQIGAAYL NDSNDDRELQ TGYKEQRWMY NWQNTTGLDS RLLAEVDYTD
ISDPYYFQDL NTDLGVRARS YVDQRGTLTY RGDSYTAKLN LHAYELANIT DITPYDRLPQ
ITLDGTLPFN PGGLKFGYST EYVRFDRDLR SGNFINEDGV IEGSWFDTRV QGLARANGER
IHVEPSVSLP LSNTWGFITP KIKYLQTNYD LDLDQRGKNS LLAEQKYSSS QNRGVGMFSV
DSGLYFDRDT QYFGKAYRQT LEPRLFYLYV PNEDQTDIPV FDSAETSFSY SSLWRENRFT
GKDRIGDENR LSLGVTSRWI EPNGFERQRV SVGQAIYLAD RKVQMPGIDY RDRAEAQSDV
SPYALEYLYR FNRDWRFTSD FNWDPDAGRT RSGSAMFHYQ PEDNVNKVVN LGYRYRNDTM
RYDQASGTWS YGGDYGTPGS PEYIKNYYKI DQHDFSVIWP LVPQWSLISR WQYDYGRNRT
LEAFGGFEYD SCCWKLRLIN RYWISYDEVS LDPARNDEGD RGIFLQIVLK GLGGVTGNKV
ETFLDQGIQG YREREDKAF
//
