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Database: UniProt
Entry: A0A0T9R005_9GAMM
LinkDB: A0A0T9R005_9GAMM
Original site: A0A0T9R005_9GAMM 
ID   A0A0T9R005_9GAMM        Unreviewed;       350 AA.
AC   A0A0T9R005;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   18-SEP-2019, entry version 18.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   Name=aroG {ECO:0000313|EMBL:CNI36617.1};
GN   ORFNames=ERS008529_03810 {ECO:0000313|EMBL:CNI36617.1};
OS   Yersinia pekkanenii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=1288385 {ECO:0000313|EMBL:CNI36617.1, ECO:0000313|Proteomes:UP000045840};
RN   [1] {ECO:0000313|Proteomes:UP000045840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A125KOH2 {ECO:0000313|Proteomes:UP000045840};
RG   Pathogen Informatics;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CQAZ01000044; CNI36617.1; -; Genomic_DNA.
DR   RefSeq; WP_049614687.1; NZ_CWJL01000008.1.
DR   EnsemblBacteria; CNI36617; CNI36617; ERS008529_03810.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000045840; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000045840};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156, ECO:0000313|EMBL:CNI36617.1}.
FT   DOMAIN       38    338       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   350 AA;  38320 MW;  A477F7B938943CE2 CRC64;
     MNYLNDDLRI NEIKELLPPV ALLEKFPASE KAAATVSKTR TAIHNILRAQ DDRLLVVIGP
     CSIHDTQAAK EYATRLLALR QELQGELEVV MRVYFEKPRT TVGWKGLIND PHMDGSYDIN
     DGLRIARKLL LDINDSGLPA AGEFLDMITP QYLADLMSWG AIGARTTESQ VHRELASGLS
     CPVGFKNGTD GTIKVAIDAI NAASAPHCFL SVTKWGHSAI VNTAGNDDCH IILRGGKEPN
     YSSVHVAEVK EGLSNAGLEP QIMIDFSHAN SSKQFKKQME VATDVCRQIA QGEKSIMGVM
     IESHLVEGNQ NLESSEPLTY GKSVTDACIG WEDTETVLRQ LASAVRARRQ
//
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