ID A0A0U1KKT9_9BACI Unreviewed; 518 AA.
AC A0A0U1KKT9;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Malate-2H(+)/Na(+)-lactate antiporter {ECO:0000313|EMBL:CQR46552.1};
GN Name=mleN_1 {ECO:0000313|EMBL:CQR46552.1};
GN ORFNames=BN1058_00819 {ECO:0000313|EMBL:CQR46552.1};
OS Paraliobacillus sp. PM-2.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Paraliobacillus.
OX NCBI_TaxID=1462524 {ECO:0000313|EMBL:CQR46552.1, ECO:0000313|Proteomes:UP000199066};
RN [1] {ECO:0000313|EMBL:CQR46552.1, ECO:0000313|Proteomes:UP000199066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PM-2 {ECO:0000313|EMBL:CQR46552.1,
RC ECO:0000313|Proteomes:UP000199066};
RA Murphy D.;
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CTEI01000001; CQR46552.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U1KKT9; -.
DR STRING; 1462524.BN1058_00819; -.
DR OrthoDB; 9762978at2; -.
DR Proteomes; UP000199066; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR PANTHER; PTHR43478; NA+/H+ ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43478:SF1; NA_H_ANTIPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199066};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 468..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..487
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 518 AA; 55987 MW; 2460163A30F7CF72 CRC64;
MEATIYSLIP AILMLILVLL TRKILLSLGT GIIVGALLLH EFNIFASLKQ IWIVFRDIFY
VIDEGWNFSN LYLLGFLLLL GITTAFMTAS GGSKAFGEWA IRRVKTRRGA QLIPSVLGIL
IFIDDYFNSL AVGQVARPVT DRFKISRAKL AYIIDSTSAP ITVITPISSW GAYIIGTLGS
IFAAAEITAF QPLEAFVRMV PLNFYAFAAI ISVFIVALFN FNFGLMRKHE ETAISTGELY
DKTKGNIAGD LQSELTPHKN GKMRHLLLPI GTLVLITVIV MLITGYLATE GQVTIFTLFA
NTDVNLSLFI GGLAAVLISL CLSLMQGSSS STTLLIFKEG IKSMLPAIYI LILAWMIGSI
IDLIGTGAYL AEVVERLSFN TDYLALLLFL VAGFMALSTG TSWGTFGIML PIAAQIAFAY
DIDLVLPAMA AVLAGSVFGD HCSPISDTSI LSSTGAGSNH IDHVLTQIPY ALLSALAAGI
GYVIYGFTHQ TFVALLATII TMVVLLFTLG SIVKKKRT
//
