ID   A0A0U1LLB6_TALIS        Unreviewed;       655 AA.
AC   A0A0U1LLB6;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Signal recognition particle subunit SRP72 {ECO:0000256|ARBA:ARBA00018350, ECO:0000256|PIRNR:PIRNR038922};
GN   ORFNames=PISL3812_00468 {ECO:0000313|EMBL:CRG83120.1};
OS   Talaromyces islandicus (Penicillium islandicum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Islandici.
OX   NCBI_TaxID=28573 {ECO:0000313|EMBL:CRG83120.1, ECO:0000313|Proteomes:UP000054383};
RN   [1] {ECO:0000313|EMBL:CRG83120.1, ECO:0000313|Proteomes:UP000054383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WF-38-12 {ECO:0000313|EMBL:CRG83120.1};
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the signal recognition particle (SRP) complex, a
CC       ribonucleoprotein complex that mediates the cotranslational targeting
CC       of secretory and membrane proteins to the endoplasmic reticulum (ER).
CC       {ECO:0000256|PIRNR:PIRNR038922}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC       ECO:0000256|PIRNR:PIRNR038922}. Endoplasmic reticulum
CC       {ECO:0000256|ARBA:ARBA00004240}.
CC   -!- SIMILARITY: Belongs to the SRP72 family.
CC       {ECO:0000256|ARBA:ARBA00007676, ECO:0000256|PIRNR:PIRNR038922}.
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DR   EMBL; CVMT01000001; CRG83120.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0U1LLB6; -.
DR   STRING; 28573.A0A0U1LLB6; -.
DR   OMA; NDMKVLA; -.
DR   OrthoDB; 91080at2759; -.
DR   Proteomes; UP000054383; Unassembled WGS sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005786; C:signal recognition particle, endoplasmic reticulum targeting; IEA:UniProtKB-UniRule.
DR   GO; GO:0008312; F:7S RNA binding; IEA:InterPro.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR013699; Signal_recog_part_SRP72_RNA-bd.
DR   InterPro; IPR026270; SRP72.
DR   InterPro; IPR031545; SRP72_TPR-like.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR14094; SIGNAL RECOGNITION PARTICLE 72; 1.
DR   PANTHER; PTHR14094:SF9; SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72; 1.
DR   Pfam; PF08492; SRP72; 1.
DR   Pfam; PF17004; SRP_TPR_like; 1.
DR   PIRSF; PIRSF038922; SRP72; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR038922};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054383};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW   ECO:0000256|PIRNR:PIRNR038922};
KW   Signal recognition particle {ECO:0000256|ARBA:ARBA00023135,
KW   ECO:0000256|PIRNR:PIRNR038922}.
FT   DOMAIN          556..603
FT                   /note="Signal recognition particle SRP72 subunit RNA-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF08492"
FT   REGION          559..655
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        575..601
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        626..644
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   655 AA;  72338 MW;  259BA737B68731D9 CRC64;
     MSAATVQSLS QLLQRSSIEE HDEVLKACNA ALKKSKTDLH AQHAKVVALL KLDRYEDSLR
     VLEEAGDTLK AKAPIEYAYA LYKCGRLSEA AEIAASSATG RGAKHVEAQA NYRAEKFASV
     ATIYESLAGN EAELGNEYND LRINTWAAHA QRLWQREGDL SQIRKPTRED LEAFETAYNA
     ACASIARGDL KQGEILLKRA KELCKTSEYL SPEDKASELL PINIQQLYTL LRQGKHESAE
     EVAQEISINE DIDLSTKKIA QNNISILQQQ NTNPYQLHKL FHDAPEPSES DKLFKFQSSA
     LDGNSHALDL EVQKSDGVIR STTKALTQLP YPSVDPDVNL LSIYNAAARV QDKTGHQAIQ
     ELRSLLARRP KDIGLVLTIV QLYVGEGNTT SAINALENTI HLLEESISEA DQEIRYNPGL
     VSVLIALYQR EGRKAHVKAE LAKAASYWRQ KPAQPTSLLR AAASQLLHSS DPADLAISQQ
     LFGAIHSKNP ADKFAIAGYV ASYATTDLAK VKKELDILPK VQDLVPDDVD VAALENAGVP
     QSQASLAANA AVLAGARKRA AKDQNARAKK RIRKSRLPKD YDPSKPPDAE RWLPLRDRST
     YRPKGRKGKQ RAAERTQGFV VTEKDEAALQ QQQQQQQQQQ KTASNASKKK KKGKR
//