ID   A0A0U1LQE0_TALIS        Unreviewed;       916 AA.
AC   A0A0U1LQE0;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Dynamin-type G domain-containing protein {ECO:0000259|PROSITE:PS51718};
GN   ORFNames=PISL3812_01740 {ECO:0000313|EMBL:CRG84455.1};
OS   Talaromyces islandicus (Penicillium islandicum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Islandici.
OX   NCBI_TaxID=28573 {ECO:0000313|EMBL:CRG84455.1, ECO:0000313|Proteomes:UP000054383};
RN   [1] {ECO:0000313|EMBL:CRG84455.1, ECO:0000313|Proteomes:UP000054383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WF-38-12 {ECO:0000313|EMBL:CRG84455.1};
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001270};
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004374}.
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DR   EMBL; CVMT01000001; CRG84455.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0U1LQE0; -.
DR   STRING; 28573.A0A0U1LQE0; -.
DR   OMA; RCERMIL; -.
DR   OrthoDB; 1381184at2759; -.
DR   Proteomes; UP000054383; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:UniProt.
DR   CDD; cd00882; Ras_like_GTPase; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045063; Dynamin_N.
DR   InterPro; IPR030381; G_DYNAMIN_dom.
DR   InterPro; IPR027094; Mitofusin_fam.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10465; TRANSMEMBRANE GTPASE FZO1; 1.
DR   PANTHER; PTHR10465:SF0; TRANSMEMBRANE GTPASE MARF-RELATED; 1.
DR   Pfam; PF00350; Dynamin_N; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51718; G_DYNAMIN_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054383}.
FT   DOMAIN          272..578
FT                   /note="Dynamin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51718"
FT   REGION          1..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          62..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          152..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          496..534
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          897..916
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..181
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        520..534
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   916 AA;  101271 MW;  686DB021B74D7364 CRC64;
     MAQDYYSKHG ESSSSREGSS SGRHDERDPQ EYQPGWATPQ YLTVGNGARS SAAEALVASL
     NRDSGYGDSV SGDSAMAGGD LSDWRAGLLE DQPSPAPSSA MASEGDRQMF SSQVLQYQYN
     NNRMKLGRAI TRTIETLKEL QEMNRQWPAI YPSVQPSQRP SLHHTQSDYT GTDSSGSSPS
     RPAPLKRAMT TIGEEEVAES SASADRRVST EPRLMTPQIA QEFSILKLDL KLGALSQAEL
     VHSLEKTSIA SLLDGKISQS VKHLLSLRDR IEDKSSKVLV TGDLNAGKST FCNALLRRKI
     LPEDQQPCTS IFCEVLDARE NEGVEEVHAI HKDQFYNRND ESTYDVFALS ELENIVIDNS
     KYMQCKVYVK DVRPVDESLL NNGVVDIALI DAPGLNSDSV KTTAVFARQE EIDVVVFVVS
     AANHFTLSAR DFIINAAHEK AYMFMVVNGF DNIRDKDRCQ RMILDQIGKM SPQTHKDAAE
     LVHFVSSNAI PVVPGAVMSS GSGSGGPDGD PGDDDDGDDD GSKDKGKGKE KEKIEDFEKL
     ESSLRRFVLE RRARSKLAPA KTYLLNVLAD LNALASVNRD VADSELQRVN TELEEILPAF
     EDKQKQKEVV ETSVKETIEK SWEDVYKHTR STLKQTIERV AYNDLGVSYP GLLSAFQYAE
     DLKLAMLDQI SESVSDCENY ARAKTVQGVA YVQQLGILHV GEDKFTPLSF RADNMFRKRR
     HTLARQVDAQ VELWDFVDIP GLWERQEKVA GTGFAMTAIT VLGGRAIGGF GWVDGVFGAA
     KVLGSNNMRR MIIPGMVAAA FLAVAYVLSS IPETLPPRLS RKLAESLTEV DYIHSNASRI
     ANEVRRVLWM PATNLQASLA QGIEDLGRRR EDVSKVQQES EVAKKYFANL FRESQENRRT
     VDQVELEGPL PGALTQ
//