ID A0A0U1LUU1_TALIS Unreviewed; 315 AA.
AC A0A0U1LUU1;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] {ECO:0000256|ARBA:ARBA00026117};
DE EC=1.3.1.124 {ECO:0000256|ARBA:ARBA00026117};
GN ORFNames=PISL3812_04184 {ECO:0000313|EMBL:CRG87167.1};
OS Talaromyces islandicus (Penicillium islandicum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Islandici.
OX NCBI_TaxID=28573 {ECO:0000313|EMBL:CRG87167.1, ECO:0000313|Proteomes:UP000054383};
RN [1] {ECO:0000313|EMBL:CRG87167.1, ECO:0000313|Proteomes:UP000054383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WF-38-12 {ECO:0000313|EMBL:CRG87167.1};
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (2E,4E)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(3E)-
CC enoyl-CoA + NADP(+); Xref=Rhea:RHEA:45912, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:85101,
CC ChEBI:CHEBI:85493; EC=1.3.1.124;
CC Evidence={ECO:0000256|ARBA:ARBA00024507};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (2E,4Z)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(3E)-
CC enoyl-CoA + NADP(+); Xref=Rhea:RHEA:61892, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:85099,
CC ChEBI:CHEBI:85493; EC=1.3.1.124;
CC Evidence={ECO:0000256|ARBA:ARBA00024466};
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DR EMBL; CVMT01000003; CRG87167.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U1LUU1; -.
DR STRING; 28573.A0A0U1LUU1; -.
DR OMA; IVATYAW; -.
DR OrthoDB; 2092693at2759; -.
DR Proteomes; UP000054383; Unassembled WGS sequence.
DR GO; GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IEA:InterPro.
DR GO; GO:0009062; P:fatty acid catabolic process; IEA:InterPro.
DR CDD; cd05369; TER_DECR_SDR_a; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR045017; DECR2-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43296; PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE; 1.
DR PANTHER; PTHR43296:SF2; PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING]; 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054383}.
SQ SEQUENCE 315 AA; 33223 MW; E349D3D3FFFB6CB6 CRC64;
MSLPKSEYIS DVWKDGLFKN KVVFCTGGAG TICSAQVRAL VHLGADACIV GRNAEKTETM
AKSIATARSG AKVIGIGNVD VRKYENLEAA VERCAKELGG IDFVIAGAAG NFLASINQLS
VNAFKSVMDI DILGSYHTAK ATLPYLKESA AKHRVDSKSL QPSPLGTGGR IIFISATIHY
TGIPFQTHVA VAKAGIDALS NNIALEFGPL GITSNIISPG PIAATEGVDR LVPSNDREES
IRRQPLGRFG SVRDIADSTV FLFSDSGSYV SGQILVVDGA SWRMPSSSIS SSLKYPDFLL
SGEAVANVKG KKSKL
//
