ID   A0A0U1M2V6_TALIS        Unreviewed;       507 AA.
AC   A0A0U1M2V6;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=sphingolipid C(9)-methyltransferase {ECO:0000256|ARBA:ARBA00039020};
DE            EC=2.1.1.317 {ECO:0000256|ARBA:ARBA00039020};
GN   ORFNames=PISL3812_06972 {ECO:0000313|EMBL:CRG89933.1};
OS   Talaromyces islandicus (Penicillium islandicum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Islandici.
OX   NCBI_TaxID=28573 {ECO:0000313|EMBL:CRG89933.1, ECO:0000313|Proteomes:UP000054383};
RN   [1] {ECO:0000313|EMBL:CRG89933.1, ECO:0000313|Proteomes:UP000054383}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WF-38-12 {ECO:0000313|EMBL:CRG89933.1};
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC       {ECO:0000256|ARBA:ARBA00004760}.
CC   -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC   -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC       {ECO:0000256|ARBA:ARBA00010815}.
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DR   EMBL; CVMT01000007; CRG89933.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0U1M2V6; -.
DR   STRING; 28573.A0A0U1M2V6; -.
DR   OMA; QRWYRIW; -.
DR   OrthoDB; 5484439at2759; -.
DR   Proteomes; UP000054383; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR45197:SF1; SPHINGOLIPID C9-METHYLTRANSFERASE A-RELATED; 1.
DR   PANTHER; PTHR45197; SYNTHASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04190)-RELATED; 1.
DR   Pfam; PF02353; CMAS; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054383};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        54..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   507 AA;  57264 MW;  A38A44150C9BAE61 CRC64;
     MASNKFDLAS DVEFIKTPPQ PPSAFEAQDC GVRTTDSPAI HNAPLPAEGP GNESFSNIVL
     GVLIVGVPWF LARLIGGGFK TKIFFGLITL FPILIAYWTY MSSFGPRIND KARLPGRPID
     SYVTFKNPED QARWKGRNKV PIQTFSELYV DGKADIKGDT LDILEYRHDW SCFSFTWDLF
     KFILFTFGPD VIFHTKEQDM EQIRPNYDNG NDHYSYFLGP RMIYTSGIIS DTTREETLEE
     LQDNKMAVVC EKLQLKEGET LLDIGCGWGT LAKFASVNYG AKVTGITIAE TGAAWATDAL
     RKAGVPEEQS KILCMDYRDA PKQKYNKISQ LEMGEHVGVR KLTGFFRQCY DMLEDDGAMY
     VQLSGLRQAW QYEDFIWGLY LNKYIFRGAD ASTPLWNYIR SLESAGFEIK SVDTVGVHYS
     ATIWRWYRNW VGNGETIKAK YGQRWYRIWE LFLAWSVIAS RQGSATCFQI LVVKNLNATH
     RIEGVGSQFG LSGALAKAKA AGKAILK
//