ID A0A0U1M7J3_TALIS Unreviewed; 558 AA.
AC A0A0U1M7J3;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Apoptosis-inducing factor 1 {ECO:0000313|EMBL:CRG91549.1};
GN ORFNames=PISL3812_08599 {ECO:0000313|EMBL:CRG91549.1};
OS Talaromyces islandicus (Penicillium islandicum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Islandici.
OX NCBI_TaxID=28573 {ECO:0000313|EMBL:CRG91549.1, ECO:0000313|Proteomes:UP000054383};
RN [1] {ECO:0000313|EMBL:CRG91549.1, ECO:0000313|Proteomes:UP000054383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WF-38-12 {ECO:0000313|EMBL:CRG91549.1};
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00006442}.
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DR EMBL; CVMT01000010; CRG91549.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U1M7J3; -.
DR STRING; 28573.A0A0U1M7J3; -.
DR OMA; RCTHYGA; -.
DR OrthoDB; 495825at2759; -.
DR Proteomes; UP000054383; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd03478; Rieske_AIFL_N; 1.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR028202; Reductase_C.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR PANTHER; PTHR43557:SF2; RIESKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF14759; Reductase_C; 1.
DR Pfam; PF00355; Rieske; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR SUPFAM; SSF50022; ISP domain; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054383}.
FT DOMAIN 10..109
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
SQ SEQUENCE 558 AA; 59929 MW; 3AD3BA162E83A73D CRC64;
MTAAAEYKLK DLTSFNDIPN LEKVESEIEG IPDTKVLVVR VDDKIHAISP RCTHYGAPLK
NGVVAPDGRI TCPWHGACFS VSTGEIEDAP APNHLNTFEV YEKDGAVYIK GEEGAIKAGQ
RDPNLKCTPS TEEKVVVIGG GSGTLGVVQT LRELKFKGSI TLLTRESNLP LDRTKLSKAL
ISDAKKIEIR PVEWYQAAGI DIVHDEVTAV DFASKTVSAK SGKSWPYTKL VLATGGIPRA
LPLEGFKTLG NIFLLRNVPD VQDILGALGT GEKKKVVVVG SSFIGMEVGN ALSKDHDVSI
VGMEKAPLER VMGEQVGKIF QRNLEKSGVK FYLDASVDKA TPSASDQTKV GAVHLKDGTV
LDADVVILGI GVRPATDYLQ NNASVSLEKD GSLRTDESFT VQGLGGDVYA IGDIATYPYH
GPGAPSDGIP VRIEHWNVAQ NAGRSVARSI THSLVSSSPL KPKAFIPVFW SALGQQLRYC
GNTTAGWDSL TLRGDPDNAK FVAYYSKAQT IVAVATMGMD PLMSKSAELM RRGNMPSKKE
IEDGVDLLKV DVPQYIAI
//
