ID A0A0U1NLX8_9RHOB Unreviewed; 454 AA.
AC A0A0U1NLX8;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Multidrug export protein MepA {ECO:0000313|EMBL:CRK75742.1};
GN Name=mepA_2 {ECO:0000313|EMBL:CRK75742.1};
GN ORFNames=NIG5292_01796 {ECO:0000313|EMBL:CRK75742.1};
OS Nereida ignava.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Nereida.
OX NCBI_TaxID=282199 {ECO:0000313|EMBL:CRK75742.1, ECO:0000313|Proteomes:UP000048949};
RN [1] {ECO:0000313|EMBL:CRK75742.1, ECO:0000313|Proteomes:UP000048949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 5292 {ECO:0000313|EMBL:CRK75742.1,
RC ECO:0000313|Proteomes:UP000048949};
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CVQV01000009; CRK75742.1; -; Genomic_DNA.
DR RefSeq; WP_048599167.1; NZ_CVQV01000009.1.
DR AlphaFoldDB; A0A0U1NLX8; -.
DR STRING; 282199.GCA_001049735_01795; -.
DR OrthoDB; 9806302at2; -.
DR Proteomes; UP000048949; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13145; MATE_like_5; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43549; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR PANTHER; PTHR43549:SF2; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000048949};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 454 AA; 48517 MW; 5D5A9FF7FC59F841 CRC64;
MQKDDLTTGP ISGHFRALAV PAAFGMLFAT LYNVVDVYFA GMLGTEAQAG LAVGYQAFFI
MMAVGFGLGS ALSALVSNAK GRKDGTSSRR LAAQGISFGL IATALLMCIG AFSGPFLIAL
VSEEGVYRDA ALGYFNWLLF ALPAFLLAYG TNGILQSHGD TVSMQRGLMV AFVANIGLTP
LFIFGIPGVW GGMGFNGIAA ATILSQTGVM IWIFSRVFAL EMMQGVPRDA FIPTWASFRE
IFAQMLPTTT ALVVMFVSGF VVQFALKGFG GEAIAAYGVG LRIEQILLLP VLGMTGALLP
IAGQNFGAGE HDRVREALRF CWKVGFVMAA IALPSLWFGG HFAMGLFTDD EAVIEIGASY
LRVDAILFPV YMMLFSINSV LQALKKPIWT LWISIYRQGL GVGLFIWVFV SLAGFDVIGV
WLGIATAVAT GWLLAMFVAG RVAEREMGGL LRAS
//
