ID A0A0U1PUG9_9MICO Unreviewed; 387 AA.
AC A0A0U1PUG9;
DT 17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT 17-FEB-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Inosine-5-monophosphate dehydrogenase {ECO:0000313|EMBL:KKM46225.1};
DE EC=1.1.1.205 {ECO:0000313|EMBL:KKM46225.1};
GN ORFNames=VT73_04025 {ECO:0000313|EMBL:KKM46225.1};
OS Rathayibacter toxicus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Rathayibacter.
OX NCBI_TaxID=145458 {ECO:0000313|EMBL:KKM46225.1, ECO:0000313|Proteomes:UP000052979};
RN [1] {ECO:0000313|EMBL:KKM46225.1, ECO:0000313|Proteomes:UP000052979}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH142 {ECO:0000313|EMBL:KKM46225.1,
RC ECO:0000313|Proteomes:UP000052979};
RG Consortium for Microbial Forensics and Genomics (microFORGE);
RA Knight B.M., Roberts D.P., Lin D., Hari K., Fletcher J., Melcher U.,
RA Blagden T., Luster D.G., Sechler A.J., Schneider W.L., Winegar R.A.;
RT "Draft genome sequence of Rathayibacter toxicus strain FH-142 (AKA 70134 or
RT CS 32), a Western Australian isolate.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the IMPDH/GMPR family.
CC {ECO:0000256|ARBA:ARBA00005502}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKM46225.1}.
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DR EMBL; LBFI01000024; KKM46225.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U1PUG9; -.
DR STRING; 145458.APU90_03470; -.
DR KEGG; rtc:APU90_03470; -.
DR PATRIC; fig|145458.8.peg.922; -.
DR eggNOG; COG0516; Bacteria.
DR Proteomes; UP000052979; Unassembled WGS sequence.
DR GO; GO:0003938; F:IMP dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd00381; IMPDH; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR005990; IMP_DH.
DR InterPro; IPR005992; IMP_DH-rel2.
DR InterPro; IPR001093; IMP_DH_GMPRt.
DR NCBIfam; TIGR01304; IMP_DH_rel_2; 1.
DR PANTHER; PTHR11911:SF111; INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11911; INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED; 1.
DR Pfam; PF00478; IMPDH; 1.
DR SMART; SM01240; IMPDH; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:KKM46225.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052979}.
FT DOMAIN 29..311
FT /note="IMP dehydrogenase/GMP reductase"
FT /evidence="ECO:0000259|Pfam:PF00478"
SQ SEQUENCE 387 AA; 40865 MW; 41ADE55100F2A872 CRC64;
MQESPVGCTA YTRQVTEIEI GRAKRARRAY AFDDIAVVPS RRTRDPEVVS VKWSIDAYQF
ETPILAAPMD SVVSPATAIT LGRLGALGVL DLEGLWTRYD EPESLLAEIR ELPAERATQR
MQEIYSAPIR PELVTARLAD IRAAGVPVAG ALSPQRTAEL HQAVVDAGVD VFVIRGTTVS
AEHVSRDKEP LNLKKFIYEL DVPVIVGGAS TYTAALHLMR TGAAGVLVGF GGGAASTTRA
TLGIQAPMAT AIADVAGARR DYLDESGGRY VHVIADGGLG TSGDIVKAIA VGADAVMLGS
ALARATDAPG GGWHWGAEAH HTQLPRGRRV QVGTVGTLEQ VLFGPTTGAC GTANLIGALR
RSMATTGYSD LKEFQRVEVV VAPYQPS
//
