ID A0A0U2UNT3_9BACL Unreviewed; 492 AA.
AC A0A0U2UNT3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=4-hydroxyphenylacetate 3-hydroxylase {ECO:0000313|EMBL:ALS27881.1};
GN ORFNames=IJ21_24850 {ECO:0000313|EMBL:ALS27881.1};
OS Paenibacillus sp. 32O-W.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1695218 {ECO:0000313|EMBL:ALS27881.1, ECO:0000313|Proteomes:UP000059673};
RN [1] {ECO:0000313|Proteomes:UP000059673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=32O-W {ECO:0000313|Proteomes:UP000059673};
RA Butler R.III., Wang J., Stark B.C., Pombert J.-F.;
RT "Complete genome sequences of two moderately thermophilic Paenibacillus
RT species.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ALS27881.1, ECO:0000313|Proteomes:UP000059673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=32O-W {ECO:0000313|EMBL:ALS27881.1,
RC ECO:0000313|Proteomes:UP000059673};
RX PubMed=26868401;
RA Butler R.R.III., Wang J., Stark B.C., Pombert J.F.;
RT "Complete Genome Sequences of Two Interactive Moderate Thermophiles,
RT Paenibacillus napthalenovorans 32O-Y and Paenibacillus sp. 32O-W.";
RL Genome Announc. 4:e01717-15(2016).
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DR EMBL; CP013653; ALS27881.1; -; Genomic_DNA.
DR RefSeq; WP_062492862.1; NZ_CP013653.1.
DR AlphaFoldDB; A0A0U2UNT3; -.
DR STRING; 1695218.IJ21_24850; -.
DR KEGG; pow:IJ21_24850; -.
DR PATRIC; fig|1695218.3.peg.2644; -.
DR OrthoDB; 9785230at2; -.
DR Proteomes; UP000059673; Chromosome.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000059673}.
FT DOMAIN 7..272
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 287..478
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 156..159
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 193
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 454..457
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 492 AA; 54668 MW; 11088387E50F0818 CRC64;
MNPTTPGQHY RTRLNDGRTV WLAGERIADV PGHPAFKGTV DTVSSLLDLQ EKPDTRDDLT
FVSPGSGKPV NAAFLAPFGK EDILRRHTAF RIWSDATFGM MSRLSEYSRS LLTGWYASRH
RLGGDARKGF ADKIARYYEQ SRDGDWLSTT ALHDPQIDRS KGPSEAGDPD AYLRVVKQNR
EGIWVRGAKM IATAAPYVDE IFVFPFHRRS SADLAYSTMF AVPVGTPGLH VVCRESFASD
RHEDYPLSSK YDEMDAVIIF DDAFVPWERV FIHDDPDAIW QLRQDPAAVA LSQHQTVVRL
ISKLKFVAAV ANEISTAIGV THHLHVQEKL GELLVQVETI KALLAVSEEL AEPDGETGVW
LPAIDPLTTA RNLGSRYYPR AIGILRHLAA GGLMQTPATV AELDGPIGPL VQKYYRGADI
PASERVRLFK LAWDLIASPL GSRHELYEIF YSGDPVRTYA AQYLGYDKAK LTDPVWKLIG
NAANDRVPAA KE
//
