ID   A0A0U2WS78_9ENTE        Unreviewed;       430 AA.
AC   A0A0U2WS78;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Zinc protease {ECO:0000313|EMBL:ALS36425.1};
GN   ORFNames=ATZ35_04385 {ECO:0000313|EMBL:ALS36425.1};
OS   Enterococcus rotai.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=118060 {ECO:0000313|EMBL:ALS36425.1, ECO:0000313|Proteomes:UP000067523};
RN   [1] {ECO:0000313|EMBL:ALS36425.1, ECO:0000313|Proteomes:UP000067523}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 26678 {ECO:0000313|EMBL:ALS36425.1,
RC   ECO:0000313|Proteomes:UP000067523};
RA   Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261}.
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DR   EMBL; CP013655; ALS36425.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0U2WS78; -.
DR   STRING; 118060.ATZ35_04385; -.
DR   Proteomes; UP000067523; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:ALS36425.1};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          63..148
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          182..364
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   COILED          337..364
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   430 AA;  49165 MW;  52DB1860E6F40EAD CRC64;
     MHKKEYPQIN EVLYTEVLEN GLTVYLLPKA EYNKTYGLFT TNYGSIDNEF VPIGEKDFVK
     VPDGIAHFLE HKMFEKEDGD VFQQFGRQGA SANAFTSFTK TSYLFSTTDQ VEKNLETLIN
     FVQEPYFTKE TVDKEKGIIG QEIQMYLDDS NWRLFFGTLG NLYPKHPLHI DIAGTVESIG
     EITAKDLYTC YNTFYHPSNM TLFVVGKMDP EAMMTFIRDN QAAKTFTKAE PIKRHFPKET
     AADIIKESSL EMTISRSKVI VGLKGLDEVP TDGKELLKYK TTANLLFQLL FGNTSQNYLN
     LYNEGLLDDS FGYEFNLDRS FHFADFGGDS DQPEVLAERI EEILLTANES LEVTEENLSL
     LKKKMIGKYF QSLNSLEYIA NQFSQSLYGE TTLFDTPEVI ESVQLSDVKN LAQTLINQDG
     LSRFFMYPKK
//