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Database: UniProt
Entry: A0A0U2XLQ5_9BACL
LinkDB: A0A0U2XLQ5_9BACL
Original site: A0A0U2XLQ5_9BACL 
ID   A0A0U2XLQ5_9BACL        Unreviewed;       447 AA.
AC   A0A0U2XLQ5;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   16-JAN-2019, entry version 24.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AUO94_00250 {ECO:0000313|EMBL:ALS77168.1};
OS   Planococcus kocurii.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Planococcaceae;
OC   Planococcus.
OX   NCBI_TaxID=1374 {ECO:0000313|EMBL:ALS77168.1, ECO:0000313|Proteomes:UP000065533};
RN   [1] {ECO:0000313|EMBL:ALS77168.1, ECO:0000313|Proteomes:UP000065533}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43650 {ECO:0000313|EMBL:ALS77168.1,
RC   ECO:0000313|Proteomes:UP000065533};
RA   See-Too W.S.;
RT   "Complete genome of Planococcus kocurri type strain.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP013661; ALS77168.1; -; Genomic_DNA.
DR   RefSeq; WP_058383852.1; NZ_CP013661.2.
DR   EnsemblBacteria; ALS77168; ALS77168; AUO94_00250.
DR   KEGG; pku:AUO94_00250; -.
DR   KO; K02313; -.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000065533; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000065533};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      143    271       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      355    424       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     151    158       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      424    447       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   447 AA;  50753 MW;  81B0CBB848B62C81 CRC64;
     MEHLDELWSS VLAQVETKIS KPSFETWLKS TKLLSYQDDT VTISAPNSFA RDWLENHYVH
     LITGILSDST GDDMMIKFVV PKDQDMDDFQ LPAPRVKPGQ DQQQEFLPGM LNPKYTFDTF
     VIGSGNRFAH AASLAVAEAP AKAYNPLFIY GGVGLGKTHL MHAIGHYVLE HNPNAKVVYL
     SSEKFTNEFI NSIRDNKTGE FRDKYRGVDI LLIDDIQFLA GKEQTQEEFF HTFNTLHEES
     KQIIISSDRP PKEIPTLEDR LRSRFEWGLI TDITPPDLET RIAILRKKAK ADGLDIPNDV
     MTYIANSIDS NIRELEGALI RVVAYSSLIN RDMSAELAAE ALKDIMPNSK PKVITILDIQ
     HAVGDQFNVK LEDFKTKRRT KDIAYPRQVA MYLSREMTDF SLPKIGEEFG GRDHTTVIHA
     HDKISKMLKD NQQLQQDVKD IKNALGK
//
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