ID A0A0U2Z3T1_9BACL Unreviewed; 841 AA.
AC A0A0U2Z3T1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN ORFNames=AUC31_00340 {ECO:0000313|EMBL:ALS73788.1};
OS Planococcus rifietoensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae; Planococcus.
OX NCBI_TaxID=200991 {ECO:0000313|EMBL:ALS73788.1, ECO:0000313|Proteomes:UP000067683};
RN [1] {ECO:0000313|EMBL:ALS73788.1, ECO:0000313|Proteomes:UP000067683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M8 {ECO:0000313|EMBL:ALS73788.1,
RC ECO:0000313|Proteomes:UP000067683};
RA See-Too W.S.;
RT "Complete genome of Planococcus rifietoensis type strain M8.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
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DR EMBL; CP013659; ALS73788.1; -; Genomic_DNA.
DR RefSeq; WP_058380498.1; NZ_CP013659.2.
DR AlphaFoldDB; A0A0U2Z3T1; -.
DR STRING; 200991.AUC31_00340; -.
DR KEGG; prt:AUC31_00340; -.
DR OrthoDB; 9802448at2; -.
DR Proteomes; UP000067683; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR002093; BRCA2_repeat.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50138; BRCA2_REPEAT; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000067683};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 674..690
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 600..607
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 841 AA; 94393 MW; 6DA33FE0853D8CEC CRC64;
MAPTPMIQQY LQVKSEYQDA FLFFRLGDFY EMFYDDAIKA SQLLEITLTS RGGNGEDRIP
MCGVPHHSAK NYIDQLIQKG HKVAVCEQVE DPKTTKGVVK REVVRLITPG THTEGKSVDA
KANNFIAAAD EVAGGFGLAY LDISTGESTA TYIAGNEKAL LNELQALHIR ELVVSEQLRL
LLAEEDQQLI LSVEHMEAPF TAEPALFANC PSELEMCGKR LLAYIAATQK QSLGHIQPFA
FRENARILGI DYYSKRNLEL IESIRGGDNK GTLLWLLDET VTAMGSRKLK QWLHQPLADR
FAIEARQQMV EALMDRYFVR VELQQLLKQV YDLERLSGRV AFGSASGRDL AQLRNSLEKI
PELVRELEDS GHASLEQFSA GLDPCPEVCE LLAAISDNPP LSAKEGGIIR DGFNAQLDEY
RDASRNGKDW IAELEQKERA KTGIRSLKIG YNRIFGYYIE ISKANMHLAD LERYERKQTL
ANAERYITPE LKEKETLILT AEEKSLTLEY ELFVSVREQV KEYISRIQQL ASKVSALDVY
ISFSEVAEKY RFTKPVFNDG RKISIREGRH PVVEKMLNKQ HYVPNDCELG DDGNMLLITG
PNMSGKSTYM RQVALTIVLA QIGSYVPAAS AELPIVDQIF TRIGAADDLV SGQSTFMVEM
MESQYAITHA TERSLLLFDE IGRGTSTYDG MALAQSMIEY IHEQIGANTL FSTHYHELTA
LEETLPKLSN VHVSAMEQSG KVVFLHKVKR GPADKSYGVH VAELANLPEA ILRRARELLL
SFEADNHKTQ QQAEQLSFFD ERDTVNEEVL QTIKDASISR MTPLEALQLI NDLQEKISGG
G
//
