ID A0A0U3D948_9BURK Unreviewed; 350 AA.
AC A0A0U3D948;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:ALT78443.1};
GN ORFNames=AT984_15860 {ECO:0000313|EMBL:ALT78443.1};
OS Paucibacter sp. KCTC 42545.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Roseateles.
OX NCBI_TaxID=1768242 {ECO:0000313|EMBL:ALT78443.1, ECO:0000313|Proteomes:UP000056576};
RN [1] {ECO:0000313|EMBL:ALT78443.1, ECO:0000313|Proteomes:UP000056576}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 42545 {ECO:0000313|EMBL:ALT78443.1,
RC ECO:0000313|Proteomes:UP000056576};
RA Kim S.-G., Lee Y.-J.;
RT "Complete genome of Paucibacter sp. KCTC 42545.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP013692; ALT78443.1; -; Genomic_DNA.
DR RefSeq; WP_058720927.1; NZ_CP013692.1.
DR AlphaFoldDB; A0A0U3D948; -.
DR STRING; 1768242.AT984_15860; -.
DR KEGG; pkt:AT984_15860; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000056576; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000056576}.
FT DOMAIN 255..349
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 225..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 39297 MW; B5A0804E27A83BB1 CRC64;
MNSSTKGLIP ATILTGFLGS GKTTLLKRVL SEAHGQKIAV IENEFGEETI DTDILRVDSE
EQIIQMNNGC VCCTIREDLR TTLSDLAAKR RKGELQFDRV IIETTGLADP GPVAQTFFMD
DEIAESYLLD SILTLVDAKH AENQLNDRQE ARRQIGFADQ IFISKSDLVD EASVAALTHR
IKHMNPRAPV HKAHFGEAPL NQIFDLRGFN LNAKLEIDPD FLKVDEPHDH DHHDHDHEHG
EHCDHPHHHA HEDDVKSFVF RSDRAFNPAK LEDFLGAIVQ VYGPKMLRYK GVLYMKGSDK
KVIFQGVHQL MGSDLGPKWM PGEKKASKMV FIGIDLPKEI LLQGMEGCLV
//
