ID   A0A0U3E8E1_9EURY        Unreviewed;       305 AA.
AC   A0A0U3E8E1;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=glutamine--fructose-6-phosphate transaminase (isomerizing) {ECO:0000256|ARBA:ARBA00012916};
DE            EC=2.6.1.16 {ECO:0000256|ARBA:ARBA00012916};
GN   ORFNames=sm9_1451 {ECO:0000313|EMBL:ALT69232.1};
OS   Methanobrevibacter millerae.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX   NCBI_TaxID=230361 {ECO:0000313|EMBL:ALT69232.1, ECO:0000313|Proteomes:UP000067738};
RN   [1] {ECO:0000313|EMBL:ALT69232.1, ECO:0000313|Proteomes:UP000067738}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SM9 {ECO:0000313|EMBL:ALT69232.1,
RC   ECO:0000313|Proteomes:UP000067738};
RA   Leahy S.C., Kelly W.J., Pacheco D.M., Li D., Altermann E., Attwood G.T.;
RT   "The complete genome sequence of the rumen methanogen Methanobrevibacter
RT   millerae SM9.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-
CC         phosphate + L-glutamate; Xref=Rhea:RHEA:13237, ChEBI:CHEBI:29985,
CC         ChEBI:CHEBI:58359, ChEBI:CHEBI:58725, ChEBI:CHEBI:61527; EC=2.6.1.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001031};
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DR   EMBL; CP011266; ALT69232.1; -; Genomic_DNA.
DR   RefSeq; WP_058739478.1; NZ_CP011266.1.
DR   AlphaFoldDB; A0A0U3E8E1; -.
DR   GeneID; 26736398; -.
DR   KEGG; mmil:sm9_1451; -.
DR   PATRIC; fig|230361.4.peg.1497; -.
DR   OrthoDB; 372195at2157; -.
DR   Proteomes; UP000067738; Chromosome.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 2.
DR   InterPro; IPR017932; GATase_2_dom.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   PANTHER; PTHR10937; GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING; 1.
DR   PANTHER; PTHR10937:SF0; GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING); 1.
DR   Pfam; PF13537; GATase_7; 1.
DR   SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR   PROSITE; PS51278; GATASE_TYPE_2; 1.
PE   4: Predicted;
KW   Aminotransferase {ECO:0000256|ARBA:ARBA00022576};
KW   Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962,
KW   ECO:0000313|EMBL:ALT69232.1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ALT69232.1}.
FT   DOMAIN          2..305
FT                   /note="Glutamine amidotransferase type-2"
FT                   /evidence="ECO:0000259|PROSITE:PS51278"
SQ   SEQUENCE   305 AA;  34097 MW;  C43BFBD4C61585AC CRC64;
     MCGIAGVIYK DKKTHPVGDA LTSMLESLQH RGPDSAGYAI YGSLNFPENY YQLNIEVKRR
     KGTLDNLKSL LNQISPIYKE QLVGSVGDSD VYKCKIALDE YSLLQPCIRE IDELENVNVI
     NGSHSFEMIK DIGKVKDIAE RFDVSSRMGT HGIGHTRFAT ESGVDRYHAH PYQSYIIPDI
     TVVHNGQITN YWKIRDPLER KGHTFESFND TECIVHYMAD KLDQGYKLEE ALDQAVIDLD
     GPFSILVGTP NGIGIAKDKL GLRPGVMVEN EDIFAIASEE MALHDVVDSD EIEQIAPGET
     RAYTI
//