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Database: UniProt
Entry: A0A0U3EPL6_9ACTN
LinkDB: A0A0U3EPL6_9ACTN
Original site: A0A0U3EPL6_9ACTN 
ID   A0A0U3EPL6_9ACTN        Unreviewed;       231 AA.
AC   A0A0U3EPL6;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   03-JUL-2019, entry version 16.
DE   RecName: Full=Urease {ECO:0000256|SAAS:SAAS00108089};
DE            EC=3.5.1.5 {ECO:0000256|SAAS:SAAS00108089};
GN   ORFNames=AS200_15800 {ECO:0000313|EMBL:ALV33329.1};
OS   Streptomyces sp. CdTB01.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV33329.1, ECO:0000313|Proteomes:UP000068029};
RN   [1] {ECO:0000313|EMBL:ALV33329.1, ECO:0000313|Proteomes:UP000068029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CdTB01 {ECO:0000313|EMBL:ALV33329.1,
RC   ECO:0000313|Proteomes:UP000068029};
RA   Tian Y., Zhou G., Yang H., Lu X.;
RT   "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT   bacterium tolerant to cadmium.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|SAAS:SAAS01115730};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1.
CC       {ECO:0000256|SAAS:SAAS00108095}.
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DR   EMBL; CP013743; ALV33329.1; -; Genomic_DNA.
DR   RefSeq; WP_058922995.1; NZ_CP013743.1.
DR   EnsemblBacteria; ALV33329; ALV33329; AS200_15800.
DR   KEGG; scx:AS200_15800; -.
DR   KO; K14048; -.
DR   OrthoDB; 1755809at2; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000068029; Chromosome.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-EC.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000068029};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00108092};
KW   Reference proteome {ECO:0000313|Proteomes:UP000068029}.
SQ   SEQUENCE   231 AA;  23911 MW;  CECAE79220498D15 CRC64;
     MRLTPTERDR LLLFGAAELA RARRARGLRL NVPEATALIA DTVCEAARDG ARLAEAVERA
     RSVLGPADVL PGVADVVTEV HVEAVFDDGS RLAVVTDPIG GGLGEQAPGA LLPGPLHTDP
     QAAVRLTVTN TATVPVSVTS HFHFFEANPR LDFVRERAYG MRLAVPAGSS VRFGPGESLE
     VGLVPIGGAR IAVGFAGLVD GPLDAPGARE EALRRAAACG YLGVGAEGTA R
//
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