ID A0A0U3EYG9_9ACTN Unreviewed; 759 AA.
AC A0A0U3EYG9;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Molybdopterin oxidoreductase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AS200_32990 {ECO:0000313|EMBL:ALV36337.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV36337.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV36337.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV36337.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR EMBL; CP013743; ALV36337.1; -; Genomic_DNA.
DR RefSeq; WP_058925935.1; NZ_CP013743.1.
DR AlphaFoldDB; A0A0U3EYG9; -.
DR STRING; 1725411.AS200_32990; -.
DR KEGG; scx:AS200_32990; -.
DR OrthoDB; 5287431at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR CDD; cd02787; MopB_CT_ydeP; 1.
DR CDD; cd02767; MopB_ydeP; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037951; MopB_CT_YdeP.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR InterPro; IPR041953; YdeP_MopB.
DR NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT DOMAIN 120..489
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 642..749
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 759 AA; 83051 MW; 7DC48A2D102E7921 CRC64;
MATKPPKSDP VQDAPQVAEP QHAAAGLPAI GHTLRVAQRQ MGVRRTMLTL LNVNQKDGFD
CPGCAWPEPE HRHTAEFCEN GAKAVAEEAT LRRVTPEFFA AHTVADLAGR SGYWLGQQGR
LTHPVYLPEG GDRYEPVSWE RAFDIVAEEI AALGSPDEAV FYTSGRTSNE AAFLYQLFAR
ELGTNNLPDC SNMCHESSGS ALSETIGIGK GSVLLEDLYK ADLIIVAGQN PGTNHPRMLT
ALEKAKAGGA RIITVNPLPE AGLERFKNPQ TPQGVLKGAA LTDLFLQIRI GGDQALFRLL
NKLILQTEGA VDEEFVREHT HGYEEFAAAA EAADWDETLA ATGLAREEIE RALAMVLASK
RTIVCWAMGL TQHKHSVPTI REVVNFLLLR GNIGRPGAGV CPVRGHSNVQ GDRTMGIFER
PAPAFLDALE KEFGFAPPRE HGFDVVEAIR ALRDGRAKVF FAMGGNFVSA SPDTEVTEAA
MRRARLTVHV STKLNRSHVV TGARALILPT LGRTERDLQG GGEQFVTVED SMGMVHASRG
RLEPASRHLL SEPAIVCRLA RRVLGEGSTV PWEEFEKDYA TVRDRIARVV PGFQDFNARV
ARPGGFALPH APRDERRFPT KTGKANFTAA PVEYPELPEG RLLLQTLRSH DQYNTTIYGL
DDRYRGIRNG RRVVLVNPED ARRLGVADGA YVDLVGEWRD GVERRAPGFR VVHYPTARGC
AAAYYPETNV LVPLDHTADT SNTPASKSVI VRLEQSSTD
//
