ID A0A0U3G9U0_9ACTN Unreviewed; 175 AA.
AC A0A0U3G9U0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Lysine N-acyltransferase MbtK {ECO:0000256|ARBA:ARBA00020586};
DE AltName: Full=Mycobactin synthase protein K {ECO:0000256|ARBA:ARBA00031122};
GN ORFNames=AS200_28445 {ECO:0000313|EMBL:ALV35534.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV35534.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV35534.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV35534.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acyltransferase required for the direct transfer of
CC medium- to long-chain fatty acyl moieties from a carrier protein (MbtL)
CC on to the epsilon-amino group of lysine residue in the mycobactin core.
CC {ECO:0000256|ARBA:ARBA00003818}.
CC -!- PATHWAY: Siderophore biosynthesis; mycobactin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005102}.
CC -!- SIMILARITY: Belongs to the lysine N-acyltransferase MbtK family.
CC {ECO:0000256|ARBA:ARBA00009893}.
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DR EMBL; CP013743; ALV35534.1; -; Genomic_DNA.
DR RefSeq; WP_058925144.1; NZ_CP013743.1.
DR AlphaFoldDB; A0A0U3G9U0; -.
DR STRING; 1725411.AS200_28445; -.
DR KEGG; scx:AS200_28445; -.
DR OrthoDB; 5177616at2; -.
DR UniPathway; UPA00011; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0019290; P:siderophore biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.630.30; -; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR019432; Acyltransferase_MbtK/IucB-like.
DR PANTHER; PTHR31438; LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED; 1.
DR PANTHER; PTHR31438:SF1; LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED; 1.
DR Pfam; PF13523; Acetyltransf_8; 1.
DR SMART; SM01006; AlcB; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000068029};
KW Transferase {ECO:0000313|EMBL:ALV35534.1}.
FT DOMAIN 6..53
FT /note="Acyltransferase MbtK/IucB-like conserved"
FT /evidence="ECO:0000259|SMART:SM01006"
SQ SEQUENCE 175 AA; 19537 MW; 404BCE8251A04D0B CRC64;
MTFTFRPLDP LKDAELLHSW VTHPKAAFWM MRDAKLEDVE RAYMEIAADP HHHALLGLDA
DGVPAFLMEK YDPAHRELVG LYEPLPGDVG MHFLTPPTDT PVHGFTRAVI TAVMAHLFAD
PAVRRVVVEP DVANKAVHAL NAAVGFVPER EIPKPEKKAL LSFCTRERFE QAVPA
//
