ID A0A0U3N3C3_9BURK Unreviewed; 471 AA.
AC A0A0U3N3C3;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=H+/Cl-antiporter ClcA {ECO:0000313|EMBL:REG21098.1};
DE SubName: Full=Voltage gated chloride channel family protein {ECO:0000313|EMBL:ALV08676.1};
GN ORFNames=DES44_0210 {ECO:0000313|EMBL:REG21098.1}, RD2015_4229
GN {ECO:0000313|EMBL:ALV08676.1};
OS Roseateles depolymerans.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Roseateles.
OX NCBI_TaxID=76731 {ECO:0000313|EMBL:ALV08676.1, ECO:0000313|Proteomes:UP000060699};
RN [1] {ECO:0000313|EMBL:ALV08676.1, ECO:0000313|Proteomes:UP000060699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 42856 {ECO:0000313|EMBL:ALV08676.1,
RC ECO:0000313|Proteomes:UP000060699};
RA Kim K.M.;
RT "Complete genome of Roseateles depolymerans KCTC 42856.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:REG21098.1, ECO:0000313|Proteomes:UP000256283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11813 {ECO:0000313|EMBL:REG21098.1,
RC ECO:0000313|Proteomes:UP000256283};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP013729; ALV08676.1; -; Genomic_DNA.
DR EMBL; QUMT01000001; REG21098.1; -; Genomic_DNA.
DR RefSeq; WP_058937614.1; NZ_QUMT01000001.1.
DR AlphaFoldDB; A0A0U3N3C3; -.
DR KEGG; rdp:RD2015_4229; -.
DR PATRIC; fig|76731.3.peg.4333; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000060699; Chromosome.
DR Proteomes; UP000256283; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd01034; EriC_like; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000060699};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 425..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..460
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 49784 MW; 7BAA4BC86F3DFC35 CRC64;
MRHDLADWRQ WLARTVVLVY AVLAGLAVVM FTWLSDWAIE GFDHLRQWSP WAPLVWTPCC
AAALVWLTRR FAPGAAGSGI PQVMAALSPQ VPAARMGMFV SLRLSLAKLL LVSGGLLGGL
AIGREGPSVQ IAAGVMQHAQ RWLPRRSPLN HEGLLVAGGA AGIAAAFNAP LAGVMFAIEE
MTRKIEQRTS GLLIAAIVLA GLVAVSVFGN ASYFGRLRVE HLSWSHLWPG LLTVVACGLL
GGVFSRLLQR SLLGGDDRFS RLRAQYPVRF AFACGVAIAV IGWVSHGATD GSGYGYTRRL
VEGHLDLPVL YVTLRIVATW LAVWSGVPGG IFAPSLAIGA GIGSDLAQLA GPEEGAAVMI
AIGMTAFLAA VTQAPITAFI IVMEMVDGHA MVLSLMAAAL MASLMSRWIS VPIYHRLAQA
QLARLGPEPV PGPAPEPAPE PAPEPTPEPT PGPAPEAESA LRPPEDPQHK G
//
