GenomeNet

Database: UniProt
Entry: A0A0U3N5Z8_9BURK
LinkDB: A0A0U3N5Z8_9BURK
Original site: A0A0U3N5Z8_9BURK 
ID   A0A0U3N5Z8_9BURK        Unreviewed;       374 AA.
AC   A0A0U3N5Z8;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   25-OCT-2017, entry version 11.
DE   RecName: Full=Epoxyqueuosine reductase {ECO:0000256|HAMAP-Rule:MF_00916};
DE            EC=1.17.99.6 {ECO:0000256|HAMAP-Rule:MF_00916};
DE   AltName: Full=Queuosine biosynthesis protein QueG {ECO:0000256|HAMAP-Rule:MF_00916};
GN   Name=queG {ECO:0000256|HAMAP-Rule:MF_00916};
GN   ORFNames=RD2015_3167 {ECO:0000313|EMBL:ALV07627.1};
OS   Roseateles depolymerans.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Roseateles.
OX   NCBI_TaxID=76731 {ECO:0000313|EMBL:ALV07627.1, ECO:0000313|Proteomes:UP000060699};
RN   [1] {ECO:0000313|EMBL:ALV07627.1, ECO:0000313|Proteomes:UP000060699}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KCTC 42856 {ECO:0000313|EMBL:ALV07627.1,
RC   ECO:0000313|Proteomes:UP000060699};
RA   Kim K.M.;
RT   "Complete genome of Roseateles depolymerans KCTC 42856.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the conversion of epoxyqueuosine (oQ) to
CC       queuosine (Q), which is a hypermodified base found in the wobble
CC       positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
CC       {ECO:0000256|HAMAP-Rule:MF_00916}.
CC   -!- CATALYTIC ACTIVITY: Queuosine(34) in tRNA + acceptor + H(2)O =
CC       epoxyqueuosine(34) in tRNA + reduced acceptor. {ECO:0000256|HAMAP-
CC       Rule:MF_00916}.
CC   -!- PATHWAY: tRNA modification; tRNA-queuosine biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00916}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00916}.
CC   -!- SIMILARITY: Belongs to the QueG family. {ECO:0000256|HAMAP-
CC       Rule:MF_00916}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP013729; ALV07627.1; -; Genomic_DNA.
DR   RefSeq; WP_058935708.1; NZ_CP013729.1.
DR   EnsemblBacteria; ALV07627; ALV07627; RD2015_3167.
DR   KEGG; rdp:RD2015_3167; -.
DR   PATRIC; fig|76731.3.peg.3244; -.
DR   KO; K18979; -.
DR   UniPathway; UPA00392; -.
DR   Proteomes; UP000060699; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0052693; F:epoxyqueuosine reductase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008616; P:queuosine biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00916; QueG; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR   InterPro; IPR013542; DUF1730.
DR   InterPro; IPR004453; QueG.
DR   PANTHER; PTHR30002; PTHR30002; 1.
DR   Pfam; PF08331; DUF1730; 1.
DR   TIGRFAMs; TIGR00276; TIGR00276; 1.
DR   PROSITE; PS00198; 4FE4S_FER_1; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Complete proteome {ECO:0000313|Proteomes:UP000060699};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Iron {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Iron-sulfur {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Oxidoreductase {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Queuosine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00916};
KW   Reference proteome {ECO:0000313|Proteomes:UP000060699};
KW   tRNA processing {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   DOMAIN      198    227       4Fe-4S ferredoxin-type.
FT                                {ECO:0000259|PROSITE:PS51379}.
FT   METAL       207    207       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   METAL       210    210       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   METAL       213    213       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
FT   METAL       217    217       Iron-sulfur 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_00916}.
FT   METAL       260    260       Iron-sulfur 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_00916}.
FT   METAL       263    263       Iron-sulfur 2. {ECO:0000256|HAMAP-Rule:
FT                                MF_00916}.
FT   METAL       267    267       Iron-sulfur 1 (4Fe-4S).
FT                                {ECO:0000256|HAMAP-Rule:MF_00916}.
SQ   SEQUENCE   374 AA;  41799 MW;  5EFD8FA3EEA802A6 CRC64;
     MESLLNASDR TPDSLHALTG QIRTWALELG FSQIGVAHVD LGDAEAGLQA WLDAGFHGEM
     QYMAAHGMKR ARPAELVPGT LCVLTARMDY LPPSLQADWQ QREYDALADP ARAQVSLYAR
     GRDYHKVLRQ RLQQLADRIQ SAVGPLGHRV FTDSAPVLEV ELASRSGIGW RGKHTLTLHR
     EAGSMFFLGE IYLDLPLPPS EPVSAHCGQC RACLDACPTQ AIVAPYRLDA RRCISYLTIE
     QDGPIPEALR PAMGNRIYGC DDCQLACPWN KFARRQALPD FDWREPLGHA SLLQLWAWDE
     PTFLKRTEGS AIRRIGHARW RRNLAVAMGN ALRQPLAPSL RRELREALCA VQHTASPLLA
     EHIDWALRQT CDHT
//
DBGET integrated database retrieval system