ID A0A0U3NHY6_9ACTN Unreviewed; 342 AA.
AC A0A0U3NHY6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Hydroxyneurosporene methyltransferase {ECO:0000313|EMBL:ALV30859.1};
GN ORFNames=AS200_01210 {ECO:0000313|EMBL:ALV30859.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV30859.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV30859.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV30859.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP013743; ALV30859.1; -; Genomic_DNA.
DR RefSeq; WP_058920547.1; NZ_CP013743.1.
DR AlphaFoldDB; A0A0U3NHY6; -.
DR STRING; 1725411.AS200_01210; -.
DR KEGG; scx:AS200_01210; -.
DR OrthoDB; 4145676at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031725; ASMT_dimerisation.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF16864; Dimerisation2; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ALV30859.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:ALV30859.1}.
FT DOMAIN 16..91
FT /note="Acetylserotonin O-methyltransferase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16864"
FT DOMAIN 116..323
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 252
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 342 AA; 36641 MW; C7832CBAEC74F740 CRC64;
MSVLPEVRDQ SDSYALLHLI QGAVITQAVS VAARLGVADV LAGGPLSVSD IAARVGSDAQ
ATHRLLRALA GHQVFARRAD GRWENTPMSE HLREDAPDSM RGFALLMSHP TLWEEWGHLA
ATVESGEANL PKLRGMGALD FFHANLDYAR VFFEAFGGLS ASETAPILAA YDFSGFTTVV
DVIAGRGNLL AGILKQAPDT KGVLYDSKVA TVDSLALFEA AGVADRLTIE HGGYLDKLPT
GGDAYVFKHI IHDFSRADAL TALRNAREAI APGGKLLVIE YVIPENNEKH LGNTIDLWLM
LMLGAQERTL AEYTALFAEA GFKLTRAVPT SAPISLIEGI PV
//
