ID   A0A0U3NIK4_9ACTN        Unreviewed;       865 AA.
AC   A0A0U3NIK4;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=ATP-dependent helicase {ECO:0000313|EMBL:ALV36343.1};
GN   ORFNames=AS200_33020 {ECO:0000313|EMBL:ALV36343.1};
OS   Streptomyces sp. CdTB01.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV36343.1, ECO:0000313|Proteomes:UP000068029};
RN   [1] {ECO:0000313|EMBL:ALV36343.1, ECO:0000313|Proteomes:UP000068029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CdTB01 {ECO:0000313|EMBL:ALV36343.1,
RC   ECO:0000313|Proteomes:UP000068029};
RA   Tian Y., Zhou G., Yang H., Lu X.;
RT   "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT   bacterium tolerant to cadmium.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP013743; ALV36343.1; -; Genomic_DNA.
DR   RefSeq; WP_058925941.1; NZ_CP013743.1.
DR   AlphaFoldDB; A0A0U3NIK4; -.
DR   STRING; 1725411.AS200_33020; -.
DR   KEGG; scx:AS200_33020; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000068029; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17990; DEXHc_HrpB; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR010225; HrpB.
DR   InterPro; IPR049614; HrpB_DEXH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013689; RNA_helicase_ATP-dep_HrpB_C.
DR   NCBIfam; TIGR01970; DEAH_box_HrpB; 1.
DR   PANTHER; PTHR43519; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR   PANTHER; PTHR43519:SF1; ATP-DEPENDENT RNA HELICASE HRPB; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF08482; HrpB_C; 1.
DR   PIRSF; PIRSF005496; ATP_hel_hrpB; 2.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ALV36343.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT   DOMAIN          20..185
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          213..382
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          491..543
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          841..865
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   865 AA;  91362 MW;  D6A5ED2AC0931285 CRC64;
     MIRYDALDAL PVRGALPALD DALDGHGTAV LVAPPGTGKT TLVPLELSGL LGRGPARRVV
     VAEPRRIAVR AAARRMAWLL GERTGESVGY TVRGERVVGR HTRVEVVTTG VLLQRLQRDQ
     ELAGVDVVVL DECHERHLDA DTAAAFLWDV RETLRPELRL LAASATTDAE GWARLLGGAP
     VIEAEGVAHP VEVVWAPPAR PVRPPHGMRV DPALLAHVAS TVRRALAERD GDVLCFLPGV
     GEIARVAGQL GDAGGAEVLQ VHGRAPAAVQ DAVLSPGTRR RVVLATSVAE SSLTVPGVRV
     VVDSGLAREP RVDHARGLSA LTTVRASQAA GRQRAGRAGR EAPGAVYRCW AEAEDARLPR
     FPAPEIKVAD LTAFALQTAC WGDPDASGLA LLDPPPGGAM TAARAVLTAV GAVDADGRAT
     RRGTALARLG LHPRLGRALL DTSGQGAEAV ALLSEEPPRE YGDDLAAALR TARRGGDAYA
     ARWRTEVRRL RASAEGASTT AGGDRTRAGK AGMPAPGPAD RAGAGPDDRA GASGDPGRSS
     GADDRLVGLV AALAFPERVA KADGGSYLMA SGTRAELGEG SPLRGAPWLA VAVADRPVGK
     GHARVRLAAV IDEDLARRAA GSLYSEAQEV HWADGDVVAR SVRRLGAIEL AVRPLKDADP
     GLVREALVEG LREEGLGLLR WSPDAVVLRR RLAFLRQRLG EPWPDVGDDA LLARVDEWLE
     PELGRARRRA DLGRIDAGQA LARLLPWASG EAGRLDELAP ERITVPSGSR IRIDYGDPEQ
     PVLAVKLQEM FGLHASPAVA GVPLLVHLLS PAGRPVAVTA DLASFWKDGY KGVRAELRGR
     YPKHPWPEDP ATAEPTRHTN ARLRR
//