ID A0A0U3NL27_9LACT Unreviewed; 359 AA.
AC A0A0U3NL27;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=phosphomevalonate kinase {ECO:0000256|ARBA:ARBA00012958};
DE EC=2.7.4.2 {ECO:0000256|ARBA:ARBA00012958};
GN ORFNames=NY10_1277 {ECO:0000313|EMBL:ALV21885.1};
OS Carnobacterium sp. CP1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Carnobacterium.
OX NCBI_TaxID=1564681 {ECO:0000313|EMBL:ALV21885.1, ECO:0000313|Proteomes:UP000064734};
RN [1] {ECO:0000313|EMBL:ALV21885.1, ECO:0000313|Proteomes:UP000064734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CP1 {ECO:0000313|EMBL:ALV21885.1,
RC ECO:0000313|Proteomes:UP000064734};
RA Chen J., Yang J., Zhu S., Zhang D., Xiong S.;
RT "Whole genome Sequence of Carnobacterium sp. strain CP1 Isolated from
RT Amanda bay, East Antarctic.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis
CC via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate:
CC step 2/3. {ECO:0000256|ARBA:ARBA00005017}.
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DR EMBL; CP010796; ALV21885.1; -; Genomic_DNA.
DR RefSeq; WP_058919154.1; NZ_CP010796.1.
DR AlphaFoldDB; A0A0U3NL27; -.
DR STRING; 1564681.NY10_1277; -.
DR KEGG; carc:NY10_1277; -.
DR PATRIC; fig|1564681.3.peg.1276; -.
DR OrthoDB; 1522677at2; -.
DR UniPathway; UPA00057; UER00099.
DR Proteomes; UP000064734; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004631; F:phosphomevalonate kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019287; P:isopentenyl diphosphate biosynthetic process, mevalonate pathway; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.890; GHMP kinase, C-terminal domain; 1.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR035102; Phosphomevalonate_kinase.
DR InterPro; IPR005917; Pmev_kinase_bact.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR01220; Pmev_kin_Gr_pos; 1.
DR PANTHER; PTHR31814; -; 1.
DR PANTHER; PTHR31814:SF2; PHOSPHOMEVALONATE KINASE; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ALV21885.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000064734};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 114..171
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 260..332
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 359 AA; 39518 MW; C058FF5DE89BC6A1 CRC64;
MIEVSAPGKL YIAGEYAVVE PGHPAILVAI DQFITVSLEK TENVGSITSF QYGNLPVLWR
RQNDLLVLDK RENPFHYILA AINVTESYAK ELGKELSFYS LMVDSELDSS NGRKYGLGSS
AAVTVATVQA LCQYYDLGAN NETIFKLAAL AHLSVKSNGS CGDVAASVYG GWLAFTTFDR
EWVLKQQEQN QSVKTLIERE WPHLSITPLT PPLDLRLVIG WTGSPASTSH LVDEVTNQRS
RDKQAYEVFL KESALCVNRM IEAFQAGDIK AIQTQIRKNR ELLVQMSKDT GVTIETPSLT
QLCEVAETYN GAAKSSGAGG GDCGIVLFDR KEGLLSLMTA WEEKDITNLP LHVYTKAEK
//
