ID A0A0U3P2N7_9MOLU Unreviewed; 558 AA.
AC A0A0U3P2N7;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 13-SEP-2023, entry version 31.
DE RecName: Full=PTS EIIB type-1 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASO20_00015 {ECO:0000313|EMBL:ALV23066.1};
OS Mycoplasma sp. (ex Biomphalaria glabrata).
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=1749074 {ECO:0000313|EMBL:ALV23066.1, ECO:0000313|Proteomes:UP000063836};
RN [1] {ECO:0000313|Proteomes:UP000063836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Swain M.T., Geyer K., Niazi U., Hoffmann K.F.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ALV23066.1, ECO:0000313|Proteomes:UP000063836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Barreiro1 {ECO:0000313|EMBL:ALV23066.1};
RA Adema C.M.;
RT "Whole genome analysis of Biomphalaria glabrata (Mollusca, Lophotrochozoa),
RT a snail intermediate host for transmission of schistosomiasis.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP013128; ALV23066.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U3P2N7; -.
DR STRING; 1749074.ASO20_00015; -.
DR KEGG; myg:ASO20_00015; -.
DR PATRIC; fig|1749074.3.peg.3; -.
DR Proteomes; UP000063836; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000063836};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 41..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..452
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT DOMAIN 481..558
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT ACT_SITE 503
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 558 AA; 59989 MW; BFD89050A8993BD4 CRC64;
MKSISIKKNI AKPLPSKNNS SGSNQWFKKV LKRVESLGKA LLFPIASLPI VALFLRIGVW
IASYAGVDPS GNAVHDAAYY IGTLLSTPAS VVFGNLGTLF GVALAFGLSK DGKGEAALAG
FVGILAFNAL IQTGDFSITQ LIYGTDILTK EFPTIKSASV LNTGVLGGIV IGCWTAFLYN
RYSGIILHPF LSFFSGRRFV PMLVFVSTIL WAFFFSLFWI WIAKAFYELG NWMSSTATAG
GSSSLLIGVV AGLYGLINRA LLPFGMHNVL NAILWFQIPF NYNGKTYNGD INAFAAGVPG
SGMFQTGFFP AMMFGLPAAA AAMFMSSEKP HRKLAGGILI SAAGVSFLTG VTEPIEFAFL
YVAPLLYIFH AILTGLTAFI IVALDVHIGF GFSAGLFDYI ISIPNSVKLD NGNWYSGPWM
LFLIGIPTAA AYYFVFSFAI KKWNLSTIGR NDNIPATQGT ITEDVKTKGG AEISKDDQKV
AQSLKVIIAG LGGEENIKSF TSCATRLRVD IKDFAKVNQA TIKKAPGVFG TSKVGDTIQV
IVGPTAWKYE DVMKKMLG
//
