ID A0A0U3PJF1_9MICC Unreviewed; 571 AA.
AC A0A0U3PJF1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=MB46_02165 {ECO:0000313|EMBL:ALV44499.1};
OS Arthrobacter alpinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=656366 {ECO:0000313|EMBL:ALV44499.1, ECO:0000313|Proteomes:UP000055883};
RN [1] {ECO:0000313|EMBL:ALV44499.1, ECO:0000313|Proteomes:UP000055883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A3 {ECO:0000313|EMBL:ALV44499.1,
RC ECO:0000313|Proteomes:UP000055883};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP013745; ALV44499.1; -; Genomic_DNA.
DR RefSeq; WP_050070226.1; NZ_CP013745.1.
DR AlphaFoldDB; A0A0U3PJF1; -.
DR KEGG; arw:MB46_02165; -.
DR eggNOG; COG3290; Bacteria.
DR OrthoDB; 9792686at2; -.
DR Proteomes; UP000055883; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR039506; SPOB_a.
DR PANTHER; PTHR43547:SF10; SENSOR HISTIDINE KINASE DCUS; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR Pfam; PF14689; SPOB_a; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000313|EMBL:ALV44499.1};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Transferase {ECO:0000313|EMBL:ALV44499.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 439..561
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 571 AA; 60252 MW; 5BA7EA67A04478C0 CRC64;
MTQARAAVRL RFSTRVLLLQ LAVVCTVVLM TAGTFAALTY QWLGDQAEER ALAVARTVAS
SEDVRRETAV LAATPSALLT PETLAGGPLE DYATSAQDRT DALFVVVTDD AGLRLAHPNP
ALLGQKVSTD PSVALAGGEE TSQENGTLGR SARAKVPVFA PGSTTDVVGE VSVGFDSDDI
VAGMLRNIVP VALVTAASLA LAAVASTMMG ARLRRLTLGL EPEEISGLAQ DQEAVLRGVD
EGVIGISERG TITVFNEGAR RLLTPGSERE YSGLTLAESG LPDFLGTATG NYGPQEHVVD
ERVVIVTARP VRLKDRSTTP DLRLGRVIMV RDRTEVQALT RQLDAVNALG TALRAQRHEF
ANRLHTISGL LALDRTAEAR DYLGEILDSG PLNYPAEDLG LLNDPYLEAF IGAKSIEAHE
RGVELRIGPG TSIRGHITDP QDVTAVLGNL LDNAITAAVA GASPNKWVEV EVLDEYTESG
GTLHVVVADS GDGLRGEDAR IFAPGYSTAS PSTLDPIAGH GVGLALVRHL ARRRGGDVWV
AESGSPQSHG AVFCARLPGV IALESRFKEQ P
//
