ID   A0A0U3PVP1_9ACTN        Unreviewed;       954 AA.
AC   A0A0U3PVP1;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=RNA helicase {ECO:0000313|EMBL:ALV36754.1};
GN   ORFNames=AS200_35315 {ECO:0000313|EMBL:ALV36754.1};
OS   Streptomyces sp. CdTB01.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV36754.1, ECO:0000313|Proteomes:UP000068029};
RN   [1] {ECO:0000313|EMBL:ALV36754.1, ECO:0000313|Proteomes:UP000068029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CdTB01 {ECO:0000313|EMBL:ALV36754.1,
RC   ECO:0000313|Proteomes:UP000068029};
RA   Tian Y., Zhou G., Yang H., Lu X.;
RT   "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT   bacterium tolerant to cadmium.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP013743; ALV36754.1; -; Genomic_DNA.
DR   RefSeq; WP_058926345.1; NZ_CP013743.1.
DR   AlphaFoldDB; A0A0U3PVP1; -.
DR   STRING; 1725411.AS200_35315; -.
DR   KEGG; scx:AS200_35315; -.
DR   OrthoDB; 3229913at2; -.
DR   Proteomes; UP000068029; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ALV36754.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT   DOMAIN          59..217
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          338..501
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          263..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          663..702
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        265..291
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   954 AA;  105832 MW;  2AE6D409692F2093 CRC64;
     MIVLLSVGPG TLESTMTEDL SPAERYAAAR RRAAEQATAL ASFREMYDFG LDPFQIEACQ
     ALESGKGVLV AAPTGSGKTI VGEFAVHLAL LQGKKCFYTT PIKALSNQKY ADLCRRYGAA
     KVGLLTGDNS VNSEAPVVVM TTEVLRNMLY AGSQTLLGLG YVVMDEVHYL SDRFRGAVWE
     EVIIHLPESV TLVSLSATVS NAEEFGDWLD TVRGDTEVIV SEHRPVPLFQ HVLAGRRMYD
     LFEEGEGSKK AVNPDLTRLA RMEASRPSYQ DRRRGRAMRE ADRERERRQR SRVWTPGRPE
     VIERLDAEGL LPAITFIFSR AACEAAVQQC LYAGLRLNDD EARERVRALV EERTASIPSE
     DLHVLGYYEW LEGLERGIAA HHAGMLPTFK EVVEELFVRG LVKAVFATET LALGINMPAR
     SVVLEKLVKW NGEQHADITP GEYTQLTGRA GRRGIDVEGH AVVLWQRGMS PEHLAGLAGT
     RTYPLRSSFK PSYNMAVNLV EQFGRHRSRE LLETSFAQFQ ADKSVVGISR QVQRNEEGLE
     GYRASMTCHL GDFDEYARLR RELKDRETEL SRQGAAQRRA EAAVALEKLK PGDVIHVPTG
     KYAGLALVLD PGLPAGRSNG HRGFEHHDGP RPLVLTAERQ VKRLASIDFP VPVEALERMR
     IPKSFNPRSP QSRRDLASAL RTKAGHIPPE RARKKRSQAA DDREIARLRT AIRAHPCHGC
     SDREDHARWA ERYHRLLRDT SQLERRIEGR TNTIARTFDR IVALLTELDY LRADEVTEHG
     KRLARLYGEL DLLASECLRA GVWEGLAPAE LAACVSALVY EARVGDDAMA PKLPSGKAKA
     ALGEMVRIWG RLDALEEEFR ITQTEGVGQR EPDLGFAWAA YMWASGKGLD EVLREAEMPA
     GDFVRWCKQV IDVLGQISAA APVSGGEASS TVAKNARKAV DLLLRGVVAY SSVG
//