ID A0A0U3Q8V8_9ACTN Unreviewed; 697 AA.
AC A0A0U3Q8V8;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=AS200_29900 {ECO:0000313|EMBL:ALV35789.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV35789.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV35789.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV35789.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR EMBL; CP013743; ALV35789.1; -; Genomic_DNA.
DR RefSeq; WP_058925392.1; NZ_CP013743.1.
DR AlphaFoldDB; A0A0U3Q8V8; -.
DR STRING; 1725411.AS200_29900; -.
DR KEGG; scx:AS200_29900; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 179..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..300
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 513..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 611..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 215..333
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 697 AA; 72329 MW; 8FD03CE6A19F915F CRC64;
MGAARTRTRP GARRRRAVPW VVLGLWLAAL VLAGPFAGKF SGIQQNRSVD YLPDSADSTQ
VARIQDRLPG GESTDLVLVY HRDGGLTAAD REKAARQIAE VTGRYDITGH PHAVPSRDGT
TVMYPVSSTG PGQDDDKRDA FVDGVRDIAD GGAGLTVQVG GPGALNADMG EVFGSIDGTL
LYATLGVVTA LLILIYRSPF LWLVPLSVAG VAAGMAMAAG YGLHEAFGVT ITGQSGGVMT
VLVLGAGTDY ALLLISRYRE ELRRHERPYD AMRAALRGCG PAILASSGTV AAGLLCLLAA
DLNSSSGMGP VGTVGVLAAL VAMTTLLPAL LVVLGRRVFW PLIPAFGSEP KARRSLFSAM
GASAARRPAA VLAGGAVLLG ALALGAFNLP GALKQEDSFT QRPESIAAAQ TLARAYPGRS
SQPLTVIAPT GRTDAVLARA RTTDGVAQAT AGRSGSGWTE ISVYATAAPE SAGETRTIEA
LRAGLDGTYG TYVGGPSAQQ LDLADSQVRD REVVVPLVLA AVFVILVGLL RSLVAPLMLL
VAVVAVWGAA LGIGGLFFGP VLGLHGTDPG LGLLSFVFLV ALGVDYGIFL MHRMREESTA
GAEPRAAALT ALRTTGGVIA SAGVVLAATF AVLTTLPLAA LVELGFVIAV GVLLDTFLVR
TYLVTTASVL LKRRVWWPGR LSREPEPRPV RRQPETV
//
