ID A0A0U3QBH4_9ACTN Unreviewed; 397 AA.
AC A0A0U3QBH4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=3'-5' exonuclease {ECO:0000313|EMBL:ALV38515.1};
GN ORFNames=AS200_12320 {ECO:0000313|EMBL:ALV38515.1};
OS Streptomyces sp. CdTB01.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV38515.1, ECO:0000313|Proteomes:UP000068029};
RN [1] {ECO:0000313|EMBL:ALV38515.1, ECO:0000313|Proteomes:UP000068029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CdTB01 {ECO:0000313|EMBL:ALV38515.1,
RC ECO:0000313|Proteomes:UP000068029};
RA Tian Y., Zhou G., Yang H., Lu X.;
RT "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT bacterium tolerant to cadmium.";
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP013743; ALV38515.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U3QBH4; -.
DR STRING; 1725411.AS200_12320; -.
DR KEGG; scx:AS200_12320; -.
DR OrthoDB; 144122at2; -.
DR Proteomes; UP000068029; Chromosome.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR CDD; cd06142; RNaseD_exo; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR041605; Exo_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47649; RIBONUCLEASE D; 1.
DR PANTHER; PTHR47649:SF1; RIBONUCLEASE D; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF18305; DNA_pol_A_exoN; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SMART; SM00341; HRDC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000313|EMBL:ALV38515.1};
KW Hydrolase {ECO:0000313|EMBL:ALV38515.1};
KW Nuclease {ECO:0000313|EMBL:ALV38515.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000068029}.
FT DOMAIN 214..294
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 397 AA; 42742 MW; AABC81E59D8108F9 CRC64;
MLEPREGIPP VVADADALAR VIAAFAGGTG PVAVDAERAS GYRYGQRAYL VQLRREGAGT
ALIDPVACPD LSGLGEALSD VEWVLHAATQ DLPCLREIGM MPTRLFDTEL AGRLAGFPRV
GLGAMVEGVL GFVLEKGHSA VDWSTRPLPE PWLRYAALDV ELLVDLRDAL EKELDRQGKL
DWARQEFAAI AAAPPAEPRK DPWRRTSGMH KVRRRRQLAV VREMWQTRDR IAQRRDVSPG
KVLSDAAIVE AALALPADVQ ALTALNGFGN RMGRRQLEQW QAAVDRAKTL SESQLPAPGQ
PVTGPPPPRA WADKDPAAAA RLSAARAGVS ALAERLNMPQ ENLISPDTVR RVCWEPPRVA
DAESVGAALA GHGARAWQVE QVTPVLVAAL SASAQAT
//
