ID A0A0U3QEA5_9MICC Unreviewed; 656 AA.
AC A0A0U3QEA5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=MB46_05960 {ECO:0000313|EMBL:ALV45118.1};
OS Arthrobacter alpinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=656366 {ECO:0000313|EMBL:ALV45118.1, ECO:0000313|Proteomes:UP000055883};
RN [1] {ECO:0000313|EMBL:ALV45118.1, ECO:0000313|Proteomes:UP000055883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A3 {ECO:0000313|EMBL:ALV45118.1,
RC ECO:0000313|Proteomes:UP000055883};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP013745; ALV45118.1; -; Genomic_DNA.
DR RefSeq; WP_044570321.1; NZ_CP013745.1.
DR AlphaFoldDB; A0A0U3QEA5; -.
DR KEGG; arw:MB46_05960; -.
DR eggNOG; COG0365; Bacteria.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000055883; Chromosome.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 29..80
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 87..473
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 536..613
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 70809 MW; 43FC08561ACB0E03 CRC64;
MSSTSFAPES ATPRSTANHP SADDSARVNF WAEQAHRLDW AQPWHTDHTF VPAFDPASSE
LRVPTIEWFA GGKINAAVNC VDRHVTAGRG EKVALFCEGE PGDRRAITYR ELQDEVCRAA
NALLALGIGK GDRVVIYLPV IAETIIITLA VARLGAIHSL VFGGFSAEAL QFRVEDTGAK
LLVTTDGQFR RGKAVPVKAN ADAAVSGENS IEHVLVVRRT GSEIDWTEGR DIWWHDAVGG
ASTEHTAEYF DAETPLFIMY TSGTTGQPKG LVHTTGGYLT QASSSHELLF SNPDPTLRDA
DVHWCTADLA WVTAHTYEIY GPLSNGVGQV IFEGTPNTPH PGRHFEIIER YGVTSYYTAP
TLVRSLMGWF PDGVPAHHDL SSLRLLGTVG EAVNPQAWSW LRDQLGGGIL PMVDTWWQSE
TGGTILSPRP SDTTFKPGCA SRAMPGVSVR IVDDAGAVVK PDVQGLIVVD GIGPAMARTV
WGNPQRYLDS YWRKFAEQGY FLAGDGARYD ADGHIWILGR IDDVINISGH RLSTIEIESA
LVSHPSVIEA GVTPVADSLT GHAAVAFVVV HGEPEPAALE AELRAHVALK IGPVAKPAAV
VVVPDVPKTR SGKIMRRLLA QMFEGTPLGD TTSLQNEESM AGIVAAVTRY QKKDQS
//
