UniProt: A0A0U3QH46

Database: UniProt
Entry: A0A0U3QH46_9ACTN

LinkDB:  A0A0U3QH46_9ACTN 
Original site:  A0A0U3QH46_9ACTN

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Ontology (2)   
   GO (2)   
Gene (1)   
   KEGG GENES (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (6)   
   InterPro (4)   
   Pfam (1)   
   PROSITE (1)   
All databases (11)   

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ID   A0A0U3QH46_9ACTN        Unreviewed;       441 AA.
AC   A0A0U3QH46;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN   ORFNames=AS200_29850 {ECO:0000313|EMBL:ALV35780.1};
OS   Streptomyces sp. CdTB01.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1725411 {ECO:0000313|EMBL:ALV35780.1, ECO:0000313|Proteomes:UP000068029};
RN   [1] {ECO:0000313|EMBL:ALV35780.1, ECO:0000313|Proteomes:UP000068029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CdTB01 {ECO:0000313|EMBL:ALV35780.1,
RC   ECO:0000313|Proteomes:UP000068029};
RA   Tian Y., Zhou G., Yang H., Lu X.;
RT   "Complete genome sequence of the Streptomyces sp. strain CdTB01, a
RT   bacterium tolerant to cadmium.";
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC       family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
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DR   EMBL; CP013743; ALV35780.1; -; Genomic_DNA.
DR   RefSeq; WP_058925383.1; NZ_CP013743.1.
DR   AlphaFoldDB; A0A0U3QH46; -.
DR   STRING; 1725411.AS200_29850; -.
DR   KEGG; scx:AS200_29850; -.
DR   OrthoDB; 9814202at2; -.
DR   Proteomes; UP000068029; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR   InterPro; IPR029020; Ammonium/urea_transptr.
DR   InterPro; IPR001905; Ammonium_transpt.
DR   InterPro; IPR018047; Ammonium_transpt_CS.
DR   InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR   NCBIfam; TIGR00836; amt; 1.
DR   PANTHER; PTHR43029; AMMONIUM TRANSPORTER MEP2; 1.
DR   PANTHER; PTHR43029:SF10; AMMONIUM TRANSPORTER MEP2; 1.
DR   Pfam; PF00909; Ammonium_transp; 1.
DR   SUPFAM; SSF111352; Ammonium transporter; 1.
DR   PROSITE; PS01219; AMMONIUM_TRANSP; 1.
PE   3: Inferred from homology;
KW   Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW   ECO:0000256|RuleBase:RU362002};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000068029};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362002};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        51..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        107..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        176..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        209..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        238..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        266..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        290..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        322..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   TRANSMEM        363..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362002"
FT   DOMAIN          19..415
FT                   /note="Ammonium transporter AmtB-like"
FT                   /evidence="ECO:0000259|Pfam:PF00909"
SQ   SEQUENCE   441 AA;  45076 MW;  8869CE6B04BC9FC0 CRC64;
     METTVTTFAA AHADTGDTAW LLAATALVLL MTPGLALFYG GMVRTKSVLN MLMMSFVSIA
     LVTVVWLACG YSLAFGEDAG DGLIGGLKHA GMAGLGPDSV QGTVPTLLFA TFQLTFAIIT
     AALVSGAIAD RAKFSAWLVF VPLWALLVYV PVSHWVWGPG GWIAHHLGAL DFAGGLPVEI
     TSGASGLALC LVLGPRLGFK KDAMRPHNLP MVMLGAGLLW FGWFGFNAGS ALGANGLAAA
     VFLNTLAAGC TGLLGWLFVE QRRDGHPTTL GAASGAVAGL VAITPSCGSV SLLGALVVGL
     AAGAVCSYAV SWKFKLNYDD SLDVVGVHLV GGIVGTLLIG VFAEKAMTGG TEGLLYGGGL
     AQLGKQAVAV AVVGAYTFGV TYGIGKLLDK TMGFRATEEQ EHTGLDLTVH AETAYDHGVL
     GHGAPVSSSV VPSAQKVQSQ A
//

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