ID A0A0U3QX82_9MICC Unreviewed; 545 AA.
AC A0A0U3QX82;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=MB46_00955 {ECO:0000313|EMBL:ALV44293.1};
OS Arthrobacter alpinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=656366 {ECO:0000313|EMBL:ALV44293.1, ECO:0000313|Proteomes:UP000055883};
RN [1] {ECO:0000313|EMBL:ALV44293.1, ECO:0000313|Proteomes:UP000055883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A3 {ECO:0000313|EMBL:ALV44293.1,
RC ECO:0000313|Proteomes:UP000055883};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
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DR EMBL; CP013745; ALV44293.1; -; Genomic_DNA.
DR RefSeq; WP_044576918.1; NZ_CP013745.1.
DR AlphaFoldDB; A0A0U3QX82; -.
DR STRING; 656366.AS189_17920; -.
DR KEGG; arw:MB46_00955; -.
DR eggNOG; COG1061; Bacteria.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000055883; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:ALV44293.1};
KW Helicase {ECO:0000313|EMBL:ALV44293.1};
KW Hydrolase {ECO:0000313|EMBL:ALV44293.1};
KW Nucleotide-binding {ECO:0000313|EMBL:ALV44293.1}.
FT DOMAIN 192..346
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 400..545
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 545 AA; 59875 MW; FAFF76838AE6540D CRC64;
MADGPLIVQG DKTILLEVAH PDSTEARHAI ATFAELERAP EHMHSYRITP LGLWNARAAG
LDAEHVVDTL LTFSRYAVPH ALLLDIVEIM ARYGRLRLEK DPHHGLVLRS DDELILTEVL
HVRKIGALLG SRIDALTAVV HGSARGELKQ LLLKASWPAE DLAGYVDGTA HPIALNDDES
TWTLRDYQRT AVENFWAGGS GVVVLPCGAG KTIVGAAAMA ASGTTTLILV TNTLSARQWK
AELLKRTTLT ESEIGEYSGA VKEIHPVTIA TYQVLTTRRN GAYPHLELLD ANDWGLLIYD
EVHLLPAPIF RMTADLQARR RLGLTATLVR EDGREGEVFA LIGPKRYDAP WKDIEAQGYI
APADCVEVRV SLSRAERLAY ATADDAGRYR LCATSPAKSV VAQALVEAHP DEQILVIGQY
IDQLDELAAR LNAPLIKGTT PVKERERLFE EFRRGNISVL VVSKVANFSI DLPEASVAIQ
VSGAFGSRQE EAQRLGRLMR PKADGRTARF YTLVARDTVD SDFAAKRQRF LAEQGYAYRI
TDATA
//
