ID A0A0U3RHS1_9MICC Unreviewed; 541 AA.
AC A0A0U3RHS1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=MB46_04420 {ECO:0000313|EMBL:ALV44865.1};
OS Arthrobacter alpinus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Arthrobacter.
OX NCBI_TaxID=656366 {ECO:0000313|EMBL:ALV44865.1, ECO:0000313|Proteomes:UP000055883};
RN [1] {ECO:0000313|EMBL:ALV44865.1, ECO:0000313|Proteomes:UP000055883}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A3 {ECO:0000313|EMBL:ALV44865.1,
RC ECO:0000313|Proteomes:UP000055883};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP013745; ALV44865.1; -; Genomic_DNA.
DR RefSeq; WP_044571935.1; NZ_CP013745.1.
DR AlphaFoldDB; A0A0U3RHS1; -.
DR STRING; 656366.AS189_15640; -.
DR KEGG; arw:MB46_04420; -.
DR eggNOG; COG3290; Bacteria.
DR OrthoDB; 9792686at2; -.
DR Proteomes; UP000055883; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43547:SF10; SENSOR HISTIDINE KINASE DCUS; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 170..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 295..525
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 541 AA; 56811 MW; 35CA46242286C33D CRC64;
MFWRGWSIAR RLLVANLIFV VLLTAGLAVI MVSDAGSRTY EQTHQRMLSV AASIADSPMV
IAAATQPNAS AALQPYAEAV MRDAHVDFIT IMDPQGIRWT HPNPAEIGKP YVGSIAQAQA
GNTFFETTAG TLGPSVRVIV PIKNTAGTVT GMVATGMTVS NVQILVAARI PAVLGLAAAL
LVAGSLAAWA LGRYLKRVTF GWGPEELGQL FAYYESVLHS VREGLILVDT RGSIVLHNDH
AALLLGIDRP DSGLDTLKLP DSLRELLTSG RTATDEVHLA GERLLVVSQR PATLPGKHSP
AGTVATLRDH TELTALAGNL SSTQTLVEAL RSQTHEHANR LHAIISLIEL DRPREALAFA
TSDHAANVRL GGEFVDTLDE PFLAALLLGK RAQADERGVT LALTASGTLP PKTLDTRELV
TLLGNLVDNA IEAAAGQSQD PTVWVDLLVA DGALTLTVAD NGPGLPTTDL DVLGRIGTTG
KTSVAPGGRG YGIALIRRAT AALGGTITGE NDGGAVMTAV VPLGPDLETP TEIRPENRGN
Q
//
