ID   A0A0U3SMR3_9BACT        Unreviewed;      1014 AA.
AC   A0A0U3SMR3;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:ALW87462.1};
GN   ORFNames=AUC43_19195 {ECO:0000313|EMBL:ALW87462.1};
OS   Hymenobacter sedentarius.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Hymenobacter.
OX   NCBI_TaxID=1411621 {ECO:0000313|EMBL:ALW87462.1, ECO:0000313|Proteomes:UP000059542};
RN   [1] {ECO:0000313|EMBL:ALW87462.1, ECO:0000313|Proteomes:UP000059542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DG5B {ECO:0000313|EMBL:ALW87462.1,
RC   ECO:0000313|Proteomes:UP000059542};
RA   Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP013909; ALW87462.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0U3SMR3; -.
DR   STRING; 1411621.AUC43_19195; -.
DR   KEGG; hyg:AUC43_19195; -.
DR   Proteomes; UP000059542; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF28; BLR2861 PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000059542};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        319..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        369..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        446..465
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        509..526
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        838..857
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        864..884
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        890..911
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        940..963
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        969..994
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1014 AA;  111352 MW;  6EB154F11C5C70AA CRC64;
     MSLVIIIFGV IGFRYLSIRE YPSVDPPIIT VSASYTGASA DVMQGQVTEP LEEGINGIAG
     IKNLTSNSRD GRTQITVEFD LDADLESAAN DVRDKVSSAQ GRLPRDIDPP VVSKANADSQ
     PIVMTYLSSN KRTLLELTDY ANNTLKERIQ TIPGVSEVRV YGERKYSMRL WLDPVKLSAL
     RVSPVEVQQA LTRENVELPS GSVQGQSTQL TLRTMGRLSS VEDFNNLIIR KDAVSLIRLS
     DIGYAELYPE NDQTIFKVNG VPMVGLAVIP QPGSNQIDIA TEFNKRIKIY EKDLPKDLVL
     KPGFDNSIFI RKSISEVEHT IIEAFVLVVI IIFLFLRDWR STIIPVVAIP VSLVGIFFVM
     YLLNFSINVL TLLAIVLAIG LVVDDAIVVL ENIYSRIEDG EDPKTAAIKG SEEILMAVVS
     TTVVLAAVFL PVVFLTGITG RLFREFGIVV AGSVLISAFV SLTLTPMMCS RLLKREEKHN
     WFYRKTEPFF EKMIGAYQGS LQTFLRNRWM AWAMIAVTGG GIWFFMKTLP SELAPIEDRS
     RIIVNATGPE GASFEFMDKY MDQVTKLVMD SVGEKNLSSV FAVTSPGFAG GSNSGIARVL
     LVEADQREKT QDDIAKKLTN GVKRLSAART SVSQDQSIGS GGGGGLPVQF VVQTQDFEKL
     RTAVPKFLDL ARQDPTFQFV DVNLKFNKPE LRVNIDREKA QSLGVSVQSI SQTLQAGLSG
     QRYGYFIRNG KQYQIIGQVA REDRNQPLDV RLLSVKNVKG ELVQLDNVIR LEESSTPPQL
     YRFNRYNSAT FSASLAPGKT LGDGIAAMRA IAEKNLDDTF TTELSGASRD FEESSSSLLF
     AFGLALVLIY LVLAAQFESF RDPVIIMVTV PLALSGALLS LWYFNQTLNL FSQIGIIMLV
     GLVTKNGILI VEFANQRVEK ENVDYMTGLI EGATARFRPI LMTSLCAILG ILPIAIATGA
     GALSRRAMGI GVVGGLFFAT GLTLYVVPVM YSYFATAKKH KPKVAQSQPA AVPA
//