ID A0A0U4ATF0_9BACT Unreviewed; 426 AA.
AC A0A0U4ATF0;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Sodium:proton exchanger {ECO:0000313|EMBL:ALW86885.1};
GN ORFNames=AUC43_18460 {ECO:0000313|EMBL:ALW86885.1};
OS Hymenobacter sedentarius.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC Hymenobacter.
OX NCBI_TaxID=1411621 {ECO:0000313|EMBL:ALW86885.1, ECO:0000313|Proteomes:UP000059542};
RN [1] {ECO:0000313|EMBL:ALW86885.1, ECO:0000313|Proteomes:UP000059542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DG5B {ECO:0000313|EMBL:ALW86885.1,
RC ECO:0000313|Proteomes:UP000059542};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP013909; ALW86885.1; -; Genomic_DNA.
DR RefSeq; WP_068197181.1; NZ_CP013909.1.
DR AlphaFoldDB; A0A0U4ATF0; -.
DR STRING; 1411621.AUC43_18460; -.
DR KEGG; hyg:AUC43_18460; -.
DR OrthoDB; 57558at2; -.
DR Proteomes; UP000059542; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR Pfam; PF01699; Na_Ca_ex; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000059542};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..178
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 220..364
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
SQ SEQUENCE 426 AA; 45903 MW; 94D889C4683D4E40 CRC64;
MKKFALYVAL AIAATLPGFY LRLTGTHVAP VLEAAIFFVA ILGAGFLLSW GAEAAEEHVS
QGLVIGVLAL VTVLPEYAVD LYYTYQAGLH PGSAYAGFAA ANMTGANRLL IGAGWPLIVF
LYWWHSGKRA VALSWDNAAE IAYLALASLY SFVIVWKGSI GVIDFVVLVG IFAAYLWRLS
KLPKADHDEA EEAEDDDDEV GPAAVLATLP VRQQWLMMGV LTVVAVAVIV MAAEPFAESL
LAAGRDLGVN QFLLVQWVAP FASEVPEVVL VVLFVLNNRP TAALGALVSD KINQWTLLVG
MIPVVYALGA GHLTGFPLDA RQHEEFFLTA AQSLFAVALL LRLRLSLGSA AILLGLFSVQ
FALAWVFEHD EAGSVRLLTD MAWLYLVLAL GLFWWNRAGL VQYVRVGLLA RAEPSPVTDP
AVATNP
//
