ID A0A0U4CT35_9ACTN Unreviewed; 550 AA.
AC A0A0U4CT35;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=FAD-binding dehydrogenase {ECO:0000313|EMBL:ALX05820.1};
GN ORFNames=AERYTH_14510 {ECO:0000313|EMBL:ALX05820.1};
OS Aeromicrobium erythreum.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Aeromicrobium.
OX NCBI_TaxID=2041 {ECO:0000313|EMBL:ALX05820.1, ECO:0000313|Proteomes:UP000067689};
RN [1] {ECO:0000313|EMBL:ALX05820.1, ECO:0000313|Proteomes:UP000067689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR18 {ECO:0000313|EMBL:ALX05820.1,
RC ECO:0000313|Proteomes:UP000067689};
RX PubMed=1883712;
RA Miller E.S., Woese C.R., Brenner S.;
RT "Description of the erythromycin-producing bacterium Arthrobacter sp.
RT strain NRRL B-3381 as Aeromicrobium erythreum gen. nov., sp. nov.";
RL Int. J. Syst. Bacteriol. 41:363-368(1991).
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DR EMBL; CP011502; ALX05820.1; -; Genomic_DNA.
DR RefSeq; WP_067860187.1; NZ_CP011502.1.
DR AlphaFoldDB; A0A0U4CT35; -.
DR STRING; 2041.AERYTH_14510; -.
DR KEGG; aer:AERYTH_14510; -.
DR PATRIC; fig|2041.4.peg.3027; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000067689; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR014614; KsdD_DH.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PIRSF; PIRSF036654; UCP036654; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000067689}.
FT DOMAIN 4..531
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 550 AA; 59379 MW; CE56E533D59B4FC2 CRC64;
MDADVIVIGA GLAGLVAAAE AADRGRSVLL LDQEGEQNLG GQAFWSLGGL FLVDSPEQRR
MGVKDSRELA EQDWMGSAQF DRAEDAWPRR WAEAYLDFAA GEKRSWLHGM GLRLFPVVGW
AERGDGRAEG HGNSVPRFHL TWGTGPGVVA PFERRVREHV TTGRIRFAFR HQVDGLVVED
GVVVGAHGSL LEPTGVDRGV ASSRTVVGDF ELRAQAVIVT SGGIGGNHDL VRKVWPERLG
TPPATMVAGV PAHVDGRMLA VTQDAGASVI NPDRLWAYVE GLRNWDPVWE NHGIRILPGP
SSLWLDATGA RLPAPYFPGF DTLGTLRYLR GTGHDYSWFV LTQKVIEKEF ALSGSEQNPD
LTGKDVKLLL SRVRPGAPGP IEKFKTHGED FVVADTLEEL VAGMNRVGDD DATVDVDALR
RLVEARDREI DNDFTKDAQI TAMRGARRYR GDKLVRVATP HRFLDPKNGP LIAVRLNILT
RKTLGGLETD LSGRCLTSDG APLPGLYAAG EVSGFGGGGM MGYNALEGTF LGGCLFSGRV
AGRAAAERVG
//
