ID A0A0U5AGL2_9BACT Unreviewed; 289 AA.
AC A0A0U5AGL2;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=CRISPR-associated protein Cas6 {ECO:0000313|EMBL:BAU23123.1};
GN ORFNames=THC_0732 {ECO:0000313|EMBL:BAU23123.1};
OS Caldimicrobium thiodismutans.
OC Bacteria; Thermodesulfobacteriota; Thermodesulfobacteria;
OC Thermodesulfobacteriales; Thermodesulfobacteriaceae; Caldimicrobium.
OX NCBI_TaxID=1653476 {ECO:0000313|EMBL:BAU23123.1, ECO:0000313|Proteomes:UP000068196};
RN [1] {ECO:0000313|EMBL:BAU23123.1, ECO:0000313|Proteomes:UP000068196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TF1 {ECO:0000313|EMBL:BAU23123.1,
RC ECO:0000313|Proteomes:UP000068196};
RX PubMed=26842785; DOI=10.1099/ijsem.0.000947;
RA Kojima H., Umezawa K., Fukui M.;
RT "Caldimicrobium thiodismutans sp. nov., a sulfur-disproportionating
RT bacterium isolated from a hot spring, and emended description of the genus
RT Caldimicrobium.";
RL Int. J. Syst. Evol. Microbiol. 66:1828-1831(2016).
RN [2] {ECO:0000313|Proteomes:UP000068196}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TF1 {ECO:0000313|Proteomes:UP000068196};
RA Kojima H., Umezawa K., Fukui M.;
RT "Caldimicrobium thiodismutans sp. nov., a sulfur-disproportionating
RT bacterium isolated from a hot spring.";
RL Int. J. Syst. Evol. Microbiol. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE
CC family. {ECO:0000256|ARBA:ARBA00005937}.
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DR EMBL; AP014945; BAU23123.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U5AGL2; -.
DR STRING; 1653476.THC_0732; -.
DR KEGG; cthi:THC_0732; -.
DR PATRIC; fig|1653476.3.peg.755; -.
DR Proteomes; UP000068196; Chromosome.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd21140; Cas6_I-like; 1.
DR Gene3D; 3.30.70.1890; -; 1.
DR Gene3D; 3.30.70.1900; -; 1.
DR InterPro; IPR049435; Cas_Cas6_C.
DR InterPro; IPR010156; CRISPR-assoc_prot_Cas6.
DR InterPro; IPR045747; CRISPR-assoc_prot_Cas6_N_sf.
DR NCBIfam; TIGR01877; cas_cas6; 1.
DR PANTHER; PTHR36984; CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1; 1.
DR PANTHER; PTHR36984:SF1; CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1; 1.
DR Pfam; PF21350; Cas6_I-A; 1.
DR Pfam; PF01881; Cas_Cas6_C; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Reference proteome {ECO:0000313|Proteomes:UP000068196};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 125..218
FT /note="CRISPR associated protein Cas6 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01881"
SQ SEQUENCE 289 AA; 33977 MW; DF5494A3FEEC8044 CRC64;
MRLKITFCPV DKDQIILPIQ YNEILQGFIY NSLERGLAER IHNFGFEDPK TKRKFKLFTF
SRLLSLQKPL IKNGNIVFSG SFTFFVASPV KEFIQSLAQS ILTREVLTLG KVRVLLQSVE
VMSPPRYQEK IYVRTLSPIT VYSTFRKPDG KKITYYYSPF EEDFRKQILE NLNKKLRSLG
READLDGSIR PYKVSSRNQR IILYKNMVIK AWDGVFELCL PSFEPTYEEL KHLYLYTTSL
QKTRFEPTYE ELKRNASISI FSLFKSFEPT YEELKLASSK ICKTHPKMF
//
