ID A0A0U5B9V5_9MICO Unreviewed; 1217 AA.
AC A0A0U5B9V5;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=TM0106 family RecB-like nuclease {ECO:0008006|Google:ProtNLM};
GN ORFNames=MalAC0309_1748 {ECO:0000313|EMBL:BAU32596.1};
OS Microcella alkaliphila.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microcella.
OX NCBI_TaxID=279828 {ECO:0000313|EMBL:BAU32596.1, ECO:0000313|Proteomes:UP000218965};
RN [1] {ECO:0000313|Proteomes:UP000218965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM AC0309 {ECO:0000313|Proteomes:UP000218965};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAU32596.1, ECO:0000313|Proteomes:UP000218965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM AC0309 {ECO:0000313|EMBL:BAU32596.1,
RC ECO:0000313|Proteomes:UP000218965};
RA Kurata A., Hirose Y., Kishimoto N., Kobayashi T.;
RT "Microcella alkaliphila JAM AC0309 whole genome shotgun sequence.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP017315; BAU32596.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U5B9V5; -.
DR KEGG; malk:MalAC0309_1748; -.
DR OrthoDB; 9757917at2; -.
DR Proteomes; UP000218965; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17934; DEXXQc_Upf1-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR038720; YprB_RNase_H-like_dom.
DR NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF13482; RNase_H_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 330..518
FT /note="YprB ribonuclease H-like"
FT /evidence="ECO:0000259|Pfam:PF13482"
FT DOMAIN 1010..1190
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 525..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 574..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1217 AA; 131201 MW; 3794D8C2D08E8F46 CRC64;
MYLIDHGDGS QLLVTSASDL NAAAECEFGF ARRVDALLGR IEAPDEPLDA MNERTIVMGH
AHEARLIEAY RAAGSLIEID RPARGIDGML AAQQATLDAL HARTDMVVQA TFFDPEHGPD
VTPGMGLGFV GYADFLEHRG DGVYRVLDSK LARRAKVTAL MQLAAYAEQL ERLGIPVDSE
TGLILGDDEL SIHRLDDIAP VHRRQRDRMH ALLRDRARAS DVVTWRAPGL SHCGKCVWCA
DSIASHGDVW QTYGLRGGQW QKLADAGITT MNDLVTHTAA VAGIPQRTLD GLRAQAALQL
RADAGDPVPP VELIDASALD SLPAPNPGDL FFDFEGDPLY TEEGAGWWGI DYLFGVTDRD
DAFTAYWAHT FADERAALIA FLDDVDRRLA EHPDLHIYHY APYEKTHLRL LAARHGIGED
TVDRLLRDGV LVDLYAVVKR ALRIGSTSYS IKKLEPLYWP ESRLGSAVTA GDDSVAEYVR
ARELRLGGET HEAQQILDDI ADYNRIDCVS TRKLEQWLRA YPRGRGVDSG GAGGDGSGDG
DAGAGADPDA AGPDSAGADA PGAVDDRIIE TSPLHDDLTR LAANPDGSPA LEPDRTAEQR
LYAYAAAAID YHRREHKTYW WAHFDRLSSP LDEWADTRDV FIVDPDQPVT QTDWGMTGRQ
RSLRRQLRMH GQWAPGSRPS IGGQGGPFAV YEHPAPLPLN PRDPLSRPAR GITLDAAGDD
WVAITETLAT DPYTGRPVDE YRDLPAALTP AKPPPAGKQV DAIHEWGARL AITHPELPRD
AVVDLLLRRP PRTRGDVGLA AVTADEHGEP DRIRAVADSL LALDHSYLAV QGPPGTGKTY
LGSRVIARLV AEHGWRVGVV AQGHATVEHV LDAVVSAGLD GAHVAKAPKT GADPAQYATA
EWTVLGRADQ LAAWTAEQPR GYVIGGTAWD FANPARVERD SLDLLVIDEA GQYSLAATIA
ASVSARNLLL LGDPQQLPQV SQGTHPEPID GSALGYLTDG HDVLPADYGY FLAETRRVHP
ALAAHVSDLS YEGQLHAHPS AARRHLDGIA PGIHAHPVTH HGNATESAEE AAAVVALVDR
AIGRPWTDPT DGPVARGDAP RSRPLTAADI IVVTPYNAHV HAVRDALDAA GHTDTRAGTV
DKFQGQEAVI AIVTLAASSA ADAPRGLDFL LNRNRLNVAI SRAQWAAHIV HSPAIADHLP
HTPAGLAELS AFLRLID
//
