ID A0A0U5CI35_9MICO Unreviewed; 401 AA.
AC A0A0U5CI35;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=MalAC0309_2591 {ECO:0000313|EMBL:BAU33426.1};
OS Microcella alkaliphila.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microcella.
OX NCBI_TaxID=279828 {ECO:0000313|EMBL:BAU33426.1, ECO:0000313|Proteomes:UP000218965};
RN [1] {ECO:0000313|Proteomes:UP000218965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM AC0309 {ECO:0000313|Proteomes:UP000218965};
RA Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:BAU33426.1, ECO:0000313|Proteomes:UP000218965}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAM AC0309 {ECO:0000313|EMBL:BAU33426.1,
RC ECO:0000313|Proteomes:UP000218965};
RA Kurata A., Hirose Y., Kishimoto N., Kobayashi T.;
RT "Microcella alkaliphila JAM AC0309 whole genome shotgun sequence.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
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DR EMBL; AP017315; BAU33426.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0U5CI35; -.
DR KEGG; malk:MalAC0309_2591; -.
DR OrthoDB; 9806579at2; -.
DR Proteomes; UP000218965; Chromosome.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235}.
FT DOMAIN 142..392
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
FT REGION 105..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 401 AA; 41689 MW; 776519DFAB9AFFA9 CRC64;
MGFADPAHPL VALRRGDGIV GIGEVWRGEF RGASRFADAA RTWRTLADAA EVADPVHRAG
SGLVAFGSFA FADDSGAASV LVVPETIVGR RDGVAWVTRI SVTGTGEQSA DAEPVPGAGR
LPAETPIGER PRATLAAATL SRDDFVATVG RAIERIRAGD VEKVVIARDA TASIPADADR
RAIVTELAEA YPDTLAFAVD GLIGASPETL VSVHAREASA RVLAGSTARG ADAAEDAAAA
TQLATSQKDL DEHEFAVQSV LKAVRPHVTA VTASEAPFTL KLPNLWHLAT DVELELAEDS
SGLDLVAALH PTAAVAGSPT DAALALIAEL EPFDRGRYAG PVGWIDQDGD GEWVIALRCA
RIDDDGMLVA HAGAGIVIDS DPVAELAETR MKFRPIADAL R
//
