ID   A0A0U5CQN4_9BACT        Unreviewed;       670 AA.
AC   A0A0U5CQN4;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   Name=uvrD {ECO:0000313|EMBL:CUI17196.1};
GN   ORFNames=PNK_1587 {ECO:0000313|EMBL:CUI17196.1};
OS   Candidatus Protochlamydia naegleriophila.
OC   Bacteria; Chlamydiota; Chlamydiia; Parachlamydiales; Parachlamydiaceae;
OC   Protochlamydia.
OX   NCBI_TaxID=389348 {ECO:0000313|EMBL:CUI17196.1, ECO:0000313|Proteomes:UP000069902};
RN   [1] {ECO:0000313|Proteomes:UP000069902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KNic {ECO:0000313|Proteomes:UP000069902};
RA   Bertelli C.;
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|ARBA:ARBA00009922}.
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DR   EMBL; LN879502; CUI17196.1; -; Genomic_DNA.
DR   RefSeq; WP_032124214.1; NZ_LN879502.1.
DR   AlphaFoldDB; A0A0U5CQN4; -.
DR   STRING; 389348.PNK_1587; -.
DR   KEGG; pnl:PNK_1587; -.
DR   PATRIC; fig|389348.3.peg.1774; -.
DR   InParanoid; A0A0U5CQN4; -.
DR   Proteomes; UP000069902; Chromosome cPNK.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   CDD; cd17932; DEXQc_UvrD; 1.
DR   CDD; cd18807; SF1_C_UvrD; 1.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000069902}.
FT   DOMAIN          6..283
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          284..585
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   BINDING         27..34
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   670 AA;  77605 MW;  49268E4EEA8C47E7 CRC64;
     MEKQLDLLNP NQKRAAKLVD GRVLILAGAG SGKTRVLTMR MAYLIRNLGV SPKSILGLTF
     TNKAAAEMRH RLATFVDAQA AKQVMLCTFH SFCMQVLRQD IGRLGYTTKF SLYDEQDVQR
     LINMIVRDIL QHEGELPSLA STLNAIRQAK NKGLAPESIQ GTESSWHDSF AQDVYRRLQS
     SMRAYNAVDF DHLLGLTVEL FERFPDVLDR YQERFRYIMI DEYQDTNPIQ YRLASLLSAK
     YHNLCVVGDD DQSIYGWRGA DVKNILEFEN ATLIKLEQNY RSTNVILKAA NAVIDHNQQR
     HRKVLWSDKG EGKPIEVFHT PTEVDEAQAV VKRIVKMKET LGLRWRDFAI LYRSNALSRQ
     FELTLMKETW KMGDRWVQGI PYEIFGGVEF YERREVKDLC AYLRLILNPA DQEALLRIIN
     QPRRGIGEDS LDVLTAYNRL EQRPLWEVIE EVARREGQAA HLIQHGKALK GIEGFVRIIN
     EAKERFERGN LAENLKWLIE QVDYQKAIKE EVKSQQMRDF KWENVQEFVS SLVEFEQKAQ
     ANPEMSGSLE AFIGNLSLDN KLMQSTKDNR EEDKVNLLTF HSSKGLEFPV CFLVGMEDHI
     IPHEKSLKET GLEEERRLMY VAITRAQQHL NISMAKQRKR MGKDMASRPS RFLFEIPKEL
     LHMTDWRVTT
//