ID A0A0U9HNB4_9FIRM Unreviewed; 812 AA.
AC A0A0U9HNB4;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpC {ECO:0000313|EMBL:GAQ25567.1};
GN ORFNames=TSYNT_896 {ECO:0000313|EMBL:GAQ25567.1};
OS Tepidanaerobacter syntrophicus.
OC Bacteria; Bacillota; Clostridia; Thermosediminibacterales;
OC Tepidanaerobacteraceae; Tepidanaerobacter.
OX NCBI_TaxID=224999 {ECO:0000313|EMBL:GAQ25567.1};
RN [1] {ECO:0000313|EMBL:GAQ25567.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JL {ECO:0000313|EMBL:GAQ25567.1};
RA Matsuura N., Ohashi A., Tourlousse D.M., Sekiguchi Y.;
RT "Draft Genome Sequence of the Syntrophic Lactate-Degrading Bacterium
RT Tepidanaerobacter syntrophicus JLT.";
RL Genome Announc. 4:e01712-15(2016).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
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DR EMBL; DF977002; GAQ25567.1; -; Genomic_DNA.
DR RefSeq; WP_059032979.1; NZ_DUMI01000116.1.
DR AlphaFoldDB; A0A0U9HNB4; -.
DR STRING; 224999.GCA_001485475_01597; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000062160; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:GAQ25567.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}; Protease {ECO:0000313|EMBL:GAQ25567.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000062160};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT DOMAIN 414..449
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 410..459
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 812 AA; 91286 MW; C6E762A4D2531462 CRC64;
MNGRFTERAQ KVIAHAQEEA RRLNHNVVGT EHLLLGLLRE DEGIAARALK NLGVDADKVR
NQVEMMIGVG PFAVQGPIGY TPRAKRVMEL AIDESRRLGH NYVGTEHILL GLIREGEGVA
AQVLTNLGVS LDKAREEVLS LLMDAKGQTN FRKSSSTPTL NQFGRDLTEL ASEGKLDPVV
GREKEIERVI QVLTRRTKNN PCLIGEPGVG KTAVVEGLAQ KIIEQDVPEI LKDKRVVSLD
MASLVAGTKF RGEFEERLKK IMAEIKQAGN VILFIDEMHT IIGAGAAEGA IDASNILKPA
LARGEIQTIG ATTIDEYRKY IEKDPALERR FQPIMIEEPT VEETIEILKG LRDRYEAHHR
VKISDEAIEA AAKLSHRYIT DRFLPDKAID LIDEAASRVR LKTLTAPPEL RELEEELEGI
RKEKDAAIRA QEFEKAAALR DKEQEIKQKI EKLKELWQKD YNFENSTVTA EDIANIVGMW
TGIPVNRLTE EESERLLKLE EVLHNRVIGQ DEAVKAVAKA IRRAYAGLKD PARPIGSFIF
LGPTGVGKTE LARALADAMF GDEDALIRLD MSEYMEKFAV SRIVGAPPGY VGYEEGGELT
EKVRRRPYSV ILFDEIEKAH PDVFNILLQI LEDGRLTDSK GRTVDFRNTI LIMTSNVGAN
LIQKPKTLGF GPAQEESKNY EDMKSMVLEE LRKTFKPEFL NRIDEIIVFH PLSEEHIREI
VTLMIDELNK RLGEKQISIE VTDRAKDMLA KEGYDPMYGA RPLRRVIQKR IEDRLSEELL
KGNISEGDVV SIDVDENGDY VFKRKEVFTP LS
//
