ID A0A0V0J9I6_SCHSO Unreviewed; 795 AA.
AC A0A0V0J9I6;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Not3 domain-containing protein {ECO:0000313|WBParaSite:SSLN_0001540801-mRNA-1};
GN ORFNames=SSLN_LOCUS14849 {ECO:0000313|EMBL:VDM01235.1}, TR87299
GN {ECO:0000313|EMBL:JAP62353.1};
OS Schistocephalus solidus (Tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Diphyllobothriidea; Diphyllobothriidae; Schistocephalus.
OX NCBI_TaxID=70667 {ECO:0000313|EMBL:JAP62353.1};
RN [1] {ECO:0000313|EMBL:JAP62353.1}
RP NUCLEOTIDE SEQUENCE.
RA Hebert F.O., Grambauer S., Barber I., Landry C.R., Aubin-Horth N.;
RT "Reference transcriptome for the parasite Schistocephalus solidus: insights
RT into the molecular evolution of parasitism.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|WBParaSite:SSLN_0001540801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [3] {ECO:0000313|EMBL:VDM01235.1, ECO:0000313|Proteomes:UP000275846}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NST_G2 {ECO:0000313|EMBL:VDM01235.1,
RC ECO:0000313|Proteomes:UP000275846};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR005290}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005290}.
CC -!- SIMILARITY: Belongs to the CNOT2/3/5 family.
CC {ECO:0000256|ARBA:ARBA00007682, ECO:0000256|PIRNR:PIRNR005290}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GEEE01000872; JAP62353.1; -; Transcribed_RNA.
DR EMBL; UYSU01039368; VDM01235.1; -; Genomic_DNA.
DR STRING; 70667.A0A0V0J9I6; -.
DR WBParaSite; SSLN_0001540801-mRNA-1; SSLN_0001540801-mRNA-1; SSLN_0001540801.
DR Proteomes; UP000050788; Unplaced.
DR Proteomes; UP000275846; Unassembled WGS sequence.
DR GO; GO:0030015; C:CCR4-NOT core complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-UniRule.
DR GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:2000036; P:regulation of stem cell population maintenance; IEA:UniProt.
DR Gene3D; 2.30.30.1020; CCR4-NOT complex subunit 2/3/5, C-terminal domain; 1.
DR InterPro; IPR038635; CCR4-NOT_su2/3/5_C_sf.
DR InterPro; IPR012270; CCR4-NOT_su3/5.
DR InterPro; IPR040168; Not2/3/5.
DR InterPro; IPR007282; NOT2/3/5_C.
DR InterPro; IPR007207; Not_N.
DR PANTHER; PTHR23326; CCR4 NOT-RELATED; 1.
DR PANTHER; PTHR23326:SF1; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3; 1.
DR Pfam; PF04153; NOT2_3_5_C; 1.
DR Pfam; PF04065; Not3; 1.
DR PIRSF; PIRSF005290; NOT_su_3_5; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR005290};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005290};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000275846};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|PIRNR:PIRNR005290};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR005290};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR005290}.
FT DOMAIN 4..233
FT /note="CCR4-Not complex component Not N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04065"
FT DOMAIN 667..790
FT /note="NOT2/NOT3/NOT5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04153"
FT REGION 243..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..339
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 408..429
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 795 AA; 88153 MW; 7471C126FB543349 CRC64;
MADKRKLQCD IDRTLKRVQE GRTSFQEILD KFESSGSQTQ KEKFEADLKK EIKKLQRLRD
QIKTWLTYNE IKDKRALLEA RRVIEQDMER FKVIEKETKT KAYSKEGLLS SDAKKDPLQK
EKEELDEWLK QSILSLQTQS EKYEFELENL ATTGKKKRAD KERAATTEEK RRKLEFCSFH
IEKLETVMRH LDNERLDCAK VRSLKDQVEY IIECIDDVAI EQYQTLYEEL HLEDLSDVPI
NLPNTAGTVD HDNTALQTPS SKTTEDLTDV PVLLIGSSAS SNASSSRERQ KFTDDKLTIM
PPSASSASTP VKNISDGQSG RSGTSANTPK LAKGGGSNIA NQTAPSSFFA SSATVPSPNK
NISMKSFAGA TSASINAAQS ASNQATSGSR LHSHSESDAA VSGKGSKTEG ESADKTGETH
REKYAKVAAE SKAGNKSGKG GSKQDVNATE KHLTDSKSAT PTATPSKTDS KNASGKGDSG
PVDTSQKPSE ELPEEPVAVT VALSNTLPSI NTDPVVPSAS APGAVGSGKP GVFNLMPASS
SFSYPSRPKE LSDTMAVTSA MGRLSLLPTA SANSALPIGS SVPPSMLSTQ QKVGVDPAVA
AAHHQQAAVM AAVAQQQQQQ RMNAPCVVMH PRDSAAPFRN RQLDKPKHSF PPELIRQMQA
LESAYRRLPH PCDTEKSRML VYKQPINTPS YYPSEPYKGS DTEEYFMKLD AQTLFFLFYY
FEGTKAQYLA AKALKRMSWR FHTKYLMWFQ RHEEPKQITD EYESGTYIYY DFKSMSQRKR
EEFVFHYSFL EDKDF
//
