ID   A0A0V0QI24_PSEPJ        Unreviewed;      1167 AA.
AC   A0A0V0QI24;
DT   16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT   16-MAR-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN   ORFNames=PPERSA_07993 {ECO:0000313|EMBL:KRX01937.1};
OS   Pseudocohnilembus persalinus (Ciliate).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Scuticociliatia; Philasterida; Pseudocohnilembidae;
OC   Pseudocohnilembus.
OX   NCBI_TaxID=266149 {ECO:0000313|EMBL:KRX01937.1, ECO:0000313|Proteomes:UP000054937};
RN   [1] {ECO:0000313|EMBL:KRX01937.1, ECO:0000313|Proteomes:UP000054937}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=36N120E {ECO:0000313|EMBL:KRX01937.1};
RX   PubMed=26486372; DOI=10.1038/srep15470;
RA   Xiong J., Wang G., Cheng J., Tian M., Pan X., Warren A., Jiang C., Yuan D.,
RA   Miao W.;
RT   "Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus
RT   persalinus provides insight into its virulence through horizontal gene
RT   transfer.";
RL   Sci. Rep. 5:15470-15470(2015).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KRX01937.1}.
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DR   EMBL; LDAU01000160; KRX01937.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0V0QI24; -.
DR   EnsemblProtists; KRX01937; KRX01937; PPERSA_07993.
DR   InParanoid; A0A0V0QI24; -.
DR   OrthoDB; 51848at2759; -.
DR   Proteomes; UP000054937; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR002859; PKD/REJ-like.
DR   Pfam; PF02010; REJ; 2.
DR   PROSITE; PS01186; EGF_2; 1.
DR   PROSITE; PS50026; EGF_3; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054937};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        863..884
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1008..1028
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1034..1053
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1065..1089
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1101..1122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          483..515
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DISULFID        505..514
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ   SEQUENCE   1167 AA;  136974 MW;  890E0F6FF762F6AD CRC64;
     MDYENYPRYF LDEPITFNAE LNYIQCDSNA GEITYVEDQS FYTIWQIIDS TSVASDLETV
     TANYQQFISW EYDPWDLATY NGYQIRLKAT SNGVEAVQAR PFDVVEYPYL MCYIAGGSRT
     ESVNNDLLIE ANVLNFDVTD ALQNSGVTYN WRCLDVMQYN NCVDNTGTVL TFANSASLTI
     PANTLEPYQT YRFRLDASIT TPSNKQCYYI VYITILDVEQ TLQLIDFPEH IQAGSVNLND
     VFAITVDLDG FLNYDEPIYN FAFIYNDQVI ANQTVKYETF NIRLMDYFDS VIVSDPYIQL
     RISVQSPYEY QPNMMSLRLY LNYPPQNGVL AVSDAISGTA LSTSYTFQTY GWTDYNFDYS
     YRFSYYLSRD YYDEEVERGY NPLMSEMNII CDYSFRSVCS SYLPLPIQDD SDGNYYAVIM
     VQARDTLGGI SNVTQAIQIQ PSTKTRVNEI DALDSLYRKV LFSQKEEKVK KLVQIAHQLR
     QIDEEGCSVC SGNGVCDAVT QQCQCETGYY MRDCSMEKSD YDTYSTFKME VLGSLMDLRE
     KQLQLGYEEQ IVKAQYSLLD DKYLGVTFNQ TFVESYINEM DTYINSKISG KIDEIVDNNY
     IYKAKYKFDI DIDSIHRILK HLYYQFDAFA YSLNNTSYYS SRRQLDSFAE FQRLKYYKQL
     VNLTRDCGYQ LHRMTQPNDK IYIFEGKMFN DKMTVMSTKY ILDQILDYDI ETDVINFSQT
     GPDIEGDGNV HVYDVMVQGY EVNPYRYEPT FPYPEQDTQC QDIDVFRQNT PEREISIEVK
     AKYEFDAINT ENPDYNICIS RQYNGVWLPP TWTSTRCNTT VLEDSSGDYN VFCTCFDLNP
     VSVVDDYMCN FSNCQYEEDD FRWYESLMLY TLIVFFLFFW YLLYKAYIYD KIYMYKVTLE
     IPDSEEEPES EEDEKDEKDR LKVGNVFEYI QGSRRGKIKR HKKRTAGDEG EDIVVEDRGG
     KTEVDADELE QEEVYNDVYF KQNVCWAIYK LHELLEIFFF YDPDCRRVFR VFFWYSKGMF
     MAGLIGTLLD KDLYLWYIVM YIGLFINIYD GLISIMKQLM RRPQFILKII GLNLGIFSLI
     AALYMIIICN QWDNLADANE WAYIFLCLYF IDTMSWQPLL IFTKTVILNL AIGKGNRCAR
     FIKWLFIFYE ENIFFRNLLN QAKNVFG
//