ID A0A0V0QRX1_PSEPJ Unreviewed; 2961 AA.
AC A0A0V0QRX1;
DT 16-MAR-2016, integrated into UniProtKB/TrEMBL.
DT 16-MAR-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=USP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPERSA_06667 {ECO:0000313|EMBL:KRX05033.1};
OS Pseudocohnilembus persalinus (Ciliate).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Scuticociliatia; Philasterida; Pseudocohnilembidae;
OC Pseudocohnilembus.
OX NCBI_TaxID=266149 {ECO:0000313|EMBL:KRX05033.1, ECO:0000313|Proteomes:UP000054937};
RN [1] {ECO:0000313|EMBL:KRX05033.1, ECO:0000313|Proteomes:UP000054937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=36N120E {ECO:0000313|EMBL:KRX05033.1};
RX PubMed=26486372; DOI=10.1038/srep15470;
RA Xiong J., Wang G., Cheng J., Tian M., Pan X., Warren A., Jiang C., Yuan D.,
RA Miao W.;
RT "Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus
RT persalinus provides insight into its virulence through horizontal gene
RT transfer.";
RL Sci. Rep. 5:15470-15470(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KRX05033.1}.
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DR EMBL; LDAU01000110; KRX05033.1; -; Genomic_DNA.
DR EnsemblProtists; KRX05033; KRX05033; PPERSA_06667.
DR InParanoid; A0A0V0QRX1; -.
DR OMA; ANICKMQ; -.
DR OrthoDB; 178678at2759; -.
DR Proteomes; UP000054937; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF729; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 24; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000054937}.
FT DOMAIN 863..898
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1675..2048
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 1340..1363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1920..1956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2857..2932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 660..687
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1920..1937
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1938..1953
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2871..2932
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2961 AA; 350214 MW; 41CDA8E10B858414 CRC64;
MTEQLDKQLV DKIKNKEVVV LIQQYNQSQY PSYEEYGHKN EQQQQGFQQD LGEENPAAIY
KSILGQSIAM QRYINYFQEN KGFDNLIKRL QDDKNRMPIN IAIVYVQGLT HNNQDYYFSI
YFLNEFLPKL KEALYFNITK SSEANIRLIK QETYEDIKKT LYTLMEKVNF NQNEHRENQV
FLERFALQTA IICLNFDSLQ QKFCAIQWVN QVLDDSYKKI STDELKKWLL DNQIFQKIFD
EQSSHEQILI NSDILLKFML KEQMLEENHI DNLVTLCSKN QETFKCLCKV LDKVAYYLDV
KHVQFFINKM LEDKINLTKD HIELIFNIQN WIHKYNRENS ETVQSVKNQV IQFYKSLIFN
PEIQNEINQE ASQCLGKMIK SESKDAAQLI RQEMLQECLN NLEMNQSVGN SLKLIKEILN
TFYMTSFKTD PNSVQNCALK LVYEQKLLQI LLKNIQYVKQ QFKKSLQNSS STNIEKLYLE
KISERIQFIK YIIEEIVEIN NLNNTEAENQ MPYLLDFDIL NQYWQEFEQN FFVKQETDIF
YNFISDLTKN SRNVEIFLKI FEEKMFQDEN KIKNMNFNQF DCFKNLFTQI NQIKGNLLQS
KKQQDQDVYY YQQNQQFNDK DLYVYETASE EVFQKSSEFY IQINSNLSTV MELYQDQIKK
EIFNELIENF NQQNLKLNQQ KESLEFSPLI NSLYFLVTYL GESEQKGFGN LKSHSGLIQG
DLITFQLKNE FNSYKIQQDN LKIWSNQTIL ELRKQIAKIF NTQWDKTKIK VNDVLIQDRQ
NGRTISDLKL KDLDKLIVQK REIKEKNVPH AFLLEENGQY LTPKAKLVFT EIFLTFSNEK
QQMYKENCVQ FLNACFNTND QRVDSDIIQQ VYSNYDKENK GYLSISDFLR FYTEKSPKNE
DSEHVKEQNP VFKNLKQLGY RRDLKKESEI NEKFVDIQKL PRYILAQNEQ FYDKLFALLE
KTTKHNNQQA QNKIIDLLNY LPTSKKIYQE IKNFEGIINQ QKPIWAQIFQ KESDFELEYN
LVVIAHLITG GEDEIEEKSQ KNQKNQTQDQ IIENTDQVNK GEIQQSQKNE NENQGQQLKE
EEIQEMKLKK SSSLDSEQEK MLKDIQDQEL KEYFGSKDEE WSTKFIQSGG FQQLQKIFEQ
MVDQSQKIGQ KNQVNLNNQQ KNILGLILNI IKTYLTAIYS RNNLPQLFQK IAYLRLPIYN
ISLINEYLEE DKVHQNKQLH NKAQPQTSEK NLEKLLKLKK QIESANSEQD AEINVNNNDK
NNYNKGEKSL KRKYEINCAH CKGELVYKDD PYAEKQLSYI CDICCKTFDQ GEGSFHCDNC
NSDITYDVCE QCYNYEEDNQ EEGENKKDNN QCEKDQKNQE KPPKIHESIE FQILAEKLVG
NLGQTVLDSL DLKRFQEKVL NILIYIIKLP IYQEEKPILE FGLCILLANF KYSQDALKSF
MEQQQSEKLI LFGILKESEW VRELFHRFLF ILQREDESIK LWLANILINN MPNQSKETSI
ECNEFYQILC KVLENQKISQ KIDMTKLFEQ IITNIGNHQS TEISSDYSST DKILAGYLQI
AETLLTNNDL CKGKGNLASE LFNSCLFTKS EDILKSYKEE FQNNNNINPI NYFKCKLKWS
RKPVYNMVIQ LLKNNQDVAQ NFIIKDLKNL IDQVPSVNEW NYLPEKYSKS FTGFSGIHNI
QNICYMNSMI QQCFLTKYFR YGIIAANDNK EPNQVEYDGG LRDYKEQIFD DDNLLHQLQK
MFGFLLLTDR KFYNPLEFCF SMKDFDGQPC NVLIQQDSQE FLNMFFDKIE NSLKNSIWRD
LVINIFGGKM SAQLICKGCG HIKENLEKFY TWSLPVQNKT KLEQSLQSMV EGEIISDYKC
DNCQKKQDIQ KRVLMNDLPN FLVLHLQRII FDMNTFLNKK ISDKFEFPLE LDVQEYTKSH
MNKNQNQQPN LSRKTSEQIY EQQKRKDSTS KYIDNQTEEI QGQSKDYFKY KLKGVVVHSG
TAEGGHYFSY INTEGQTWRE FNDSLVREFD PKNIEKECFG GSTNNNGFYE QEKGDSSSNA
YILIYEKIEK KDMQFKIENQ EELKELTEKL KDGAISKSQI QKIQQKLSNK EQENIFIEVD
PESIKGDQIN TNLKQEVWLD NHQFLLQRFC YNEQFFDFIN GVLNSLQLPA GLNSDEIENL
NPQIYKDYQT IPKETKNMLN ALVNELIPNF IFKILVRAND NMGNVSKSFN YLVNFLRFVP
QYAGEFFISQ FDDQMEYFIN TCLIKCPDIQ VKKYVQKLII YLINFLLKFH NITSLIDHQQ
ETDQNVVIVE KINDLLIYMA DQLNYDVAKF WDKNEQYLQF WVDFINSGET QIEWCFKNDL
IARMIDFMLQ DKSPMKCYGK KQYTMGSKSE YGDEIKPDFK QIFFSINKLI SMADISTEKE
DNKKLNEDDK KKYILSENDS TCILNVNFCS KFLENKTDED CFNYIIKKSC YNNYENSKVM
AEKILDKMKQ TNAQNALWVD TFKYYMSIQD DLQDQRLEWI FGIYQVKENE EKSFALKPFY
IRLSAACIQS NSTIDNNILS FTDLLYKDSY SAYSQQQDSQ MVLIMAYLTV ADENKYIFEY
TANLPPISYL AGYKFTDSIK KYIEDYKKSI SSSQSLKQEI YDKCTYLMQK LEEKHKKYVD
EGKFLPVQQY ILGHTIETKE VSNEELIKDL FLEIKEVKIN LVENKNDINK NCTLVFPSYC
MDTDNSVDNR KIPLESNIYK IILQGKQNQH YQTSNENIDL DKLQTLVEIQ EDFFIKKYTL
KNMQNFKVNY EYFFEFDNQK ANFYANRCPI RKTIEANKEE TFIILHKRRI NEEIKGDKIN
IKILKNNSQF QNSNYNNNIN YNNKKPQIRH INYVNNEEND ENEDSKENQG RSSQEGSQED
NLSNQGDDFY YQQDTNNFGN QIQKDNEENN NNNYNQESNN NNQDNQGDDN ENSMPYINCG
ICGAKNPLTN EMCSTCTNDL F
//
